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XVIII Sympozjum <strong>PTZE</strong>, Zamość 2008<br />

DIFFUSE OPTICAL TOMOGRAPHY<br />

IN BIOMEDICAL APPLICATION<br />

Magdalena Stasiak 1 , Przemysław Berowski 2<br />

1<br />

Department of Electrical Apparatus, Technical University of Lodz,<br />

Stefanowskiego 18/22, 90-924 Lodz, e-mail: stasiak@p.lodz.pl<br />

2<br />

Electrotechnical Institute,<br />

Pożaryskiego 28, 04-703 Warsaw, e-mail: p.berowski@iel.waw.pl<br />

Diffuse optical tomography (DOT) is noninvasive, nonionizing and inexpensive<br />

technique used to measure the optical properties of physiological tissue. In the near-infrared<br />

(NIR) spectral window of 600-1000 nm, photon propagation in tissues is dominated by<br />

scattering rather than absorption. Photons experience multiple scattering events as they<br />

propagate deeply into tissue – up to 10 cm.<br />

In order to solve the forward problem the adequate model of computer simulation and<br />

methods are needed. The Finite Element Method (FEM) and also the Boundary Element<br />

Method (BEM) are the most frequently used among many others. The BEM is an interesting<br />

alternative to the more commonly used numerical methods such as FEM. The principle<br />

advantage of using BEM in EIT is that the discretization is necessary only at the boundary of<br />

analysed domain, what is connected with a significant reduction of the dimension and number<br />

of unknowns from O(N 2 ) to O(N). In this method the partial differential equations (PDE) with<br />

adequate boundary conditions are transformed into an equivalent integral equation set defined<br />

only on the surface of the considered volume. The original integral equation governing<br />

surface potential can be approximated as a summation of surface integrals of each element.<br />

In full paper the BEM approach to problems solution in diffuse optical tomography<br />

will be explained in details.<br />

References<br />

1. Aliabadi M.H., The Boundary Element Method, Volume 2, John Wiley &Sons, LTD, 2002<br />

2. Choe R.: Diffuse Optical Tomography and Spectography of Breast Cancer and Fetal Brain, Dissertation<br />

in Physics and Astronomy, University of Pennsylvania, 2005.<br />

3. de Munk J.C., Faes T.J.C., Heethaar R.M., The Boundary Element Method in the Forward and Inverse<br />

Problem of Electrical Impedance Tomography, IEEE Transactions on Biomedical Engineering, Vol. 47, No.<br />

6, pp.792-800, June 2000.<br />

4. Gibson A.P., Hebden J.C., and Arridge S.R.: Recent advances in diffuse optical imaging, Physics<br />

in Medicine and Biology, 50, R1-R43 (2005).<br />

5. Hillman E.: Development of optical tomography techniques for functional imaging of the neonatal brain,<br />

PhD dissertation, London 2001<br />

89

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