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22. Tsirigotis P, Economopoulos T, Rontogianni D, et al. T-cell-rich B-cell lymphoma. Analysis of clinicalfeatures, response to treatment, survival and comparison with diffuse large B-cell lymphoma.Oncology 2001,61:257-64.23. Diebold J, Anderson JR, Armitage JO, et al. Diffuse large B-cell lymphoma: a clinicopathologicanalysis of 444 cases classified according to the updated Kiel classification. Leuk Lymphoma2002;43:97-104.24. Muris JJ, Meijer CJ, Cillessen SA, et al. Prognostic significance of activated cytotoxic T-lymphocytesin primary nodal diffuse large B-cell lymphomas. Leukemia 2004;18:589-96.25. Colomo L, Loong F, Rives S, et al. Diffuse large B-cell lymphomas with plasmablastic differentiationrepresent a heterogeneous group of disease entities. Am J Surg Pathol 2004;28:736-47.26. Dave BJ, Nelson M, Pickering DL, et al. Cytogenetic characterization of diffuse large cell lymphomausing multi-color fluorescence in situ hybridization. Cancer Genet Cytogenet 2002;132:125-32.27. Bea S, Colomo L, Lopez-Guillermo A, et al. Clinicopathologic significance and prognostic value ofchromosomal imbalances in diffuse large B-cell lymphomas. J Clin Oncol 2004;22:3498-506.28. Berglund M, Enblad G, Flordal E, et al. Chromosomal imbalances in diffuse large B-cell lymphomadetected by comparative genomic hybridization. Mod Pathol 2002;15:807-16.29. Cigudosa JC, Parsa NZ, Louie DC, et al. Cytogenetic analysis of 363 consecutively ascertained diffuselarge B-cell lymphoma. Genes Chromosomes Cancer 1999;25:123-33.30. Dave BJ, Weisenburger DD, Higgins CM, et al. Cytogenetics and fluorescence in situ hybridizationstudies of diffuse large B-cell lymphoma in children and young adults. Cancer Genet Cytogenet2004;153:115-21.31. Rao PH, Houldsworth J, Dyomina K, et al. Chromosomal and gene amplification in diffuse large B-cell lymphoma. Blood 1998;92:234-40.32. Jerkeman M, Johansson B, Akerman M, Cavallin-Stahl E, Kristoffersson U, Mitelman F. Prognosticimplications of cytogenetic aberrations in diffuse large B-cell lymphomas. Eur J Haematol1999;62:184-90.
33. Nanjangud G, Rao PH, Hegde A, et al. Spectral karyotyping identifies new rearrangements,translocations, and clinical associations in diffuse large B-cell lymphoma. Blood 2002;99:2554-61.34. Bea S, Zettl A, Wright G, et al. Diffuse large B-cell lymphoma subgroups have distinct genetic profilesthat influence tumor biology and improve gene-expression-based survival prediction. Blood2005;106:3183-90.35. Hsi ED, Mirza I, Lozanski G, et al. A clinicopathologic evaluation of follicular lymphoma grade 3Aversus grade 3B reveals no survival differences. Arch Pathol Lab Med 2004;128:863-8.36. Chau I, Jones R, Cunningham D, et al. Outcome of follicular lymphoma grade 3: is anthracyclinenecessary as front-line therapy? Br J Cancer 2003;89:36-42.37. Hans CP, Weisenburger DD, Vose JM, et al. A significant diffuse component predicts for inferiorsurvival in grade 3 follicular lymphoma, but cytologic subtypes do not predict survival. Blood2003;101:2363-7.38. de Jong D. Molecular pathogenesis of follicular lymphoma: a cross talk of genetic and immunologicfactors. J Clin Oncol 2005;23:6358-63.39. Limpens J, Stad R, Vos C, et al. Lymphoma – associated translocation t(14;18) in blood B cells ofnormal individuals. Blood 1995;9:2528-36.40. Zha H, Raffeld M, Charboneau L, et al. Similarities of prosurvival signals in bcl-2 positive and bcl-2negative follicular lymphomas identified by reverse phase protein microarray. Lab Invest 2004;84:235-44.41. Akasaka T, Lossos IS, Levy R. Bcl-6 gene translocation in follicular lymphoma: a harbinger ofeventual transformation to diffuse aggressive lymphoma. Blood 2003;102:1443-8.42. Jardin F, Gaulard P, Buchonnet G, et al. Follicular lymphoma without t(14;18) and with BCL-6rearrangement: a lymphoma subtype with distinct pathological, molecular and clinical characteristics.Leukemia 2002;16:2309-17.43. Lestou VS, Gascoyne RD, Sehn L, et al. Multicolour fluorescence in situ hybridization analysis oft(14;18) – positive follicular lymphoma and correlation with gene expression data and clinicaloutcome. Br J Haematol 2003;122:745-59.
Page 1 and 2:
Središnja medicinska knjižnicaBor
Page 3 and 4:
Disertacija je izrađena u Odjelu z
Page 5 and 6:
3.4 Interfazna fluorescentna in sit
Page 7 and 8:
H&E - hemalaun & eozinHIV - virus h
Page 9 and 10:
klasifikacije limfoidnih neoplazmi
Page 11 and 12:
Folikularni limfom (FL) - 25% svih
Page 13 and 14:
simptoma. MPI obuhvaća dob bolesni
Page 15 and 16:
1.4 DNA microarray analiza genske e
Page 17 and 18:
molekularno različitih bolesti unu
Page 19 and 20:
Monoklonalna protutijela za pojedin
Page 21 and 22: Common acute lymphoblastic leukaemi
Page 23 and 24: Interakcijom s različitim efektors
Page 25 and 26: između fenotipskih skupina i vrije
Page 27 and 28: BCL2 protein je eksprimiran u stani
Page 29 and 30: p53 protein se imunohistokemijski n
Page 31 and 32: 2. Ciljevi istraživanja1. U primar
Page 33 and 34: uključuje - MPI score 3 - veliki i
Page 35 and 36: 3.2 Tkivni microarrayUzorci s dovol
Page 37 and 38: fenotipom, a fenotipski uzorci CD10
Page 39 and 40: Slika 1. Shematski prikaz LSI IgH p
Page 41 and 42: 3.4.3 Analiza preparataKorišten je
Page 43 and 44: 4. Rezultati4.1.1 Fenotipske karakt
Page 45 and 46: Odnos imunofenotipskih skupina GCB
Page 47 and 48: U slučajevima bez t(14;18)(q32;q21
Page 49 and 50: 4.2 Usporedba proteinske ekspresije
Page 51 and 52: Usporedbom imunofenotipskih skupina
Page 53 and 54: 4.3 Usporedba utjecaja fenotipskih
Page 55 and 56: Međutim, imunofenotipske skupine G
Page 57 and 58: Uočena je statistički značajna r
Page 59 and 60: učestalost t(14;18)(q32;q21) u GCB
Page 61 and 62: iljega, MUM1/IRF4 i BCL6. Isto tako
Page 63 and 64: kriterija, prema današnjim spoznaj
Page 65 and 66: ekspresije gena koja bi imala za po
Page 67 and 68: 7. Sažetak73 bolesnika s povećani
Page 69 and 70: 8. Summary73 patients with lymph no
Page 71: 11. Morgensztern D, Lossos IS. Mole
Page 75 and 76: 55. Bosga-Bouwer AG, van Imhoff GW,
Page 77 and 78: 78. Lossos IS, Alizadeh AA, Diehn M
Page 79 and 80: 100. Pescarmona E, De Sanctis V, Pi
Page 81 and 82: 122. Fabiani B, Delmer A, Lepage E,
Page 83 and 84: 143. Poulsen CB, Borup R, Nielsen F
Page 85 and 86: 166. Pinyol M, Hernandez L, Martine
Page 87 and 88: 189. Rubin MA, Dunn R, Strawderman
Page 89: Aktivno sam sudjelovala na 3 međun
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