Poklicne alergijske bolezni, zbornik predavanj - Bolnišnica Golnik

8. Najkrajše trajanje izpostavljenostiZa imunsko povzroèena poklicno astmo je znaèilen èas senzibilizacije od nekaj tednov do veèmesecev, iritativno povzroèena astma pa se pojavi po enkratni ali nekajkratni izpostavljenostiškodljivim dejavnikom znotraj 24 ur ali veè kot 24ur (European Commission, 1997; Brooks in sod.,1998; Bernstein in sod., 1999).9. Latentna dobaLatentna doba za imunsko obliko astme je 3 dni.10. Indukcijska dobaPri imunski obliki astme je indukcijska doba pri takojšnji reakciji nekaj minut do pol ure, pri poznireakciji od 3 do 8 ur in pri ponavljajoèi reakciji pa veè dni. Pri neimunski obliki astme se težave pojavijotakoj ali po veè urah.LITERATURA1. Aynacioglu AS, Nacak M, Filiz A, Ekinci E, Roots I. Protective role of glutathione S-transferase P1 (GSTP1)Val105Val genotype in patients with bronchial asthma. Br J Clin Pharmacol. 2004; 57:213-7.2. Bernstein IL, Chan-Yeung M, Malo JL, Bernstein DI. Definition and classification of asthma. In: Bernstein IL,Chan-Yeung M, Malo JL, Bernstein DI, eds. Asthma in the workplace. New York: Marcel Dekker Inc., 1999;p. 1–4.3. Brooks SM, Hammad Y, Ricards I, et al. Sudden and Not-So-Sudden Onset of Asthma and the Role ofAllergy. Chest 1998;113: 42–9.4. Burge S, Moscato G. Physiological Assessment : Serial Measurements of Lung Function. In:Bernstein IL,Chang Yeung M, Malo JL, eds. Asthma in the workplace. New York: Marcel Dekker 1999:193–210.5. Cartier A, Pineau L, Malo JL. Monitoring of maximum expiratory peak flow rates and histamine inhalationtests in the investigation of occupational asthma. Clin Allergy 1984; 14: 193–96.6. Cartier A. Occupational asthma: What have we learned? J Allerg Clin Immunol 1998; 102: 90–5.7. Chan-Yeung M. Assesment of Asthma in the Workplace. Chest 1995; 108: 1084–1117.8. Chan-Yeung M, Malo JL. Tables of major inducers of occupational asthma. In: Bernstein IL, Chan-Yeung M,Malo JL, Bernstein DI, eds. Asthma in the workplace. New York: Marcel Dekker Inc, 1999; pp. 683–720.9. Dykewicz MS. Occupational Asthma: A practical Approach. Allergy and Asthma Proc. 2001; 22: 225–33.10. European Commission: Information notices on diagnosis of occupational diseases. Report EUR 14768.Office for Official Publications of the European Communities Luxemburg 1997; 163-164.11. Greenland S, Rothman KJ. Concepts of interaction. In: Rothman KJ, Greenland S, editors. ModernEpidemiology Philadelphia, PA: Lippincott-Raven, 1998:329-42.12. Hemmingsen A, Fryer AA, Hepple M, Strange RC, Spiteri MA. Simultaneous identification of GSTP1Ile105>Val105 and Ala114>Val114 substitutions using an amplification refractory mutation systempolymerase chain reaction assay: studies in patients with asthma. Respir Res 2001; 2:255-60.13. Johnson A, Chang-Yeung M. Nonspecific Bronchial Hyperresponsiveness. In: Bernstein IL, Chang Yeung M,Malo JL, eds. Asthma in the workplace. New York: Marcel Dekker 1999; 173–92.14. Ketterer B. A bird’s eye view of the glutathione transferase field. Chem Biol Interact 2001; 138:27-42.15. Lee HS. Clinical Update on Occupational Asthma. Annals Academy of Medicine 2001; 30: 546–51.18