Nova antikoagualantna zdravila

Študija RE-LY ROCKET AF ARISTOTLEpogostost dogodka/letoD D V R V A V2x110mg2x150mgINR=2-320mgINR=2-32x5mgINR=2-3povprečni CHADS2 točkovnik 2,1 3,47 2,1možganska kap ± sistemskaembolija1.53% 1.11% 1.69% 1.70% 2.20% 1.27% 1.60%velika krvavitev 2.71% 3.11% 3.36% 3.60% 3.40% 2.13% 3.09%možganska krvavitev 0.12% 0.10% 0.38% 0.50% 0.70% 0.33% 0.80%GI krvavitev 1.12% 1.51% 1.02% 0.76% 0.86%miokardni infarkt 0.72% 0.74% 0.53% 0.90% 1.10% 0.53% 0.61%smrtnost 3.75% 3.64% 4.13% 1.90% 2.20% 3.52% 3.94%