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copyright © 2010 Grupa dr. A. R. Kwiecińskiego ISSN 1425-5073<br />

Piśmiennictwo<br />

1. Nowak M i wsp. Regulacyjna rola białek inhibitorowych<br />

apoptozy (IAP). Farm Przegl Nauk 2010; 8: 32-37.<br />

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cell death in vivo. Eur J Neurosci 2000; 12: 2059–<br />

2067.<br />

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(XIAP) prevents cell death in axotomized CNS neurons<br />

in vivo. Cell Death Differ 2000; 7: 815–824.<br />

4. Crocker SJ i wsp. NAIP protects nigrostriatal dopamine<br />

pathway in an intrastriatal 6-OHDA rat model of Parkinson’s<br />

disease. Eur J Neurosci 2001; 14: 391– 400.<br />

5. Sasaki H i wsp. Down-regulation of X-linked inhibitor<br />

of apoptosis protein induces apoptosis in chemoresistant<br />

human ovarian cancer cells. Cancer Res 2000; 60:<br />

5659–5666.<br />

6. Holcik M i wsp. Translational upregulation of X-linked<br />

inhibitor of apoptosis (XIAP) increases resistance to radiation<br />

induced cell. Heath Oncogene 2000; 19: 4174-4177.<br />

7. Dai Z i wsp. A comprehensive search for DNA amplification<br />

in lung cancer identifies inhibitors of apoptosis<br />

cIAP1 and cIAP2 as candidate oncogenes. Hum Mol<br />

Genet 2003; 12: 791–801.<br />

8. LaCasse EC, Mahoney DJ, Cheung HH. IAP-thargeted<br />

therapies for cancer. Oncogene 2008; 27: 6252-6275.<br />

9. Jansen B, Zangemeister-Wittke U. Antisense therapy<br />

forcancer––the time of truth. The Lancet 2002; 3:<br />

672–683.<br />

10. Lima RT i wsp. Special downregulation of bcl-2 and<br />

xIAP by RNAi enhances the effects of chemotherapeutic<br />

agents in MCF-7 humanbreast cancer cells. Cancer<br />

Gene Ther 2004; 11: 309–316.<br />

11. McManus DC i wsp. Loss of XIAP protein expression<br />

by RNAi and antisense approaches sensitizes cancer<br />

cells to functionally diverse chemotherapeutics. Oncogene<br />

2004; 23: 8105–8117.<br />

12. Amantana A i wsp. X-linked inhibitor of apoptosis protein<br />

inhibition induces apoptosis and enhances chemotherapy<br />

sensitivity in human prostate cancer cells. Mol<br />

Cancer Ther 2004; 3: 699–707.<br />

13. Danson S i wsp. IAPs as a target for anticancer therapy.<br />

Curr Cancer Drug Targets 2007; 7: 785–794.<br />

14. Brennan DJ i wsp. Altered cytoplasmic-to-nuclear ratio<br />

of survivin is a prognostic indicator in breast cancer.<br />

Clin Cancer Res 2008; 14: 2681–2689.<br />

15. Varfolomeev E i wsp. IAP antagonists induce autoubiquitination<br />

of c-IAPs, NF-kappaB activation, and TNFalpha-<br />

dependent apoptosis. Cell 2007; 131: 669–681.<br />

16. Mahoney DJ i wsp. Both cIAP1 and cIAP2 regulate<br />

TNF alpha-mediated NF-kB activation. Proc Natl Acad<br />

Sci USA 2008;105: 11778–11783.<br />

17. Cillessen SA i wsp. Small-molecule XIAP antagonist<br />

restores caspase-9 mediated apoptosis in XIAP-positive<br />

diffuse large B-cell lymphoma cells. Blood 2008; 111:<br />

369–375.<br />

18. Chen J i wsp. Design, synthesis, and characterization<br />

of new embelin derivatives as potent inhibitors of X-<br />

linked inhibitor of apoptosis protein. Bioorg Med Chem<br />

Lett 2006; 16: 5805–5808.<br />

19. Obiol-Pardo C, Granadino-Roldan JM, Rubio-Martinez<br />

J. Protein–protein recognition as a first step towards the<br />

inhibition of XIAP and Survivin anti-apoptotic proteins.<br />

J Mol Recognit 2008; 21: 190–204.<br />

20. Bauvois B, Dauzonne D. Aminopeptidase-N/CD13<br />

(EC 3.4.11.2) inhibitors: chemistry, biological evaluations,<br />

and therapeutic prospects. Med Res Rev 2006;<br />

26: 88–130.<br />

21. Sato S i wsp. Demonstration of direct binding of cIAP1<br />

degradation-promoting bestatin analogs to BIR3 domain:<br />

synthesis and application of fluorescent bestatin ester<br />

analogs. Bioorg Med Chem Lett 2008; 18: 3354–3358.<br />

22. Altieri DC. Survivin, cancer networks and pathway-directed<br />

drug discovery. Nat Rev Cancer 2008; 8: 61–70.<br />

23. Huang RC, Chang CC, Mold D. Survivin-dependent<br />

and independent pathways and the induction of cancer<br />

cell death by tetra-O-methyl nordihydroguaiaretic acid.<br />

Semin Oncol 2006; 33: 479–485.<br />

24. Plescia J i wsp. Rational design of shepherdin, a novel<br />

anticancer agent. Cancer Cell 2005; 7: 457–468.<br />

25. Meli M i wsp. Small-molecule targeting of heat shock<br />

protein 90 chaperone function: rational identification<br />

of a new anticancer lead. J Med Chem 2006; 49:<br />

7721–7730.<br />

26. Towler MC, Hardie DG. AMP-activated protein kinase<br />

in metabolic control and insulin signaling. Circ Res<br />

2007; 100: 328–341.<br />

27. O’Connor DS i wsp. Regulation of apoptosis at cell<br />

division by p34cdc2 phosphorylation of survivin. Proc<br />

Natl Acad Sci USA 2000; 24: 13103–13107.<br />

28. Mesri M i wsp. Cancer gene therapy using a survivin<br />

mutant adenovirus. J Clin Invest 2001; 108: 981–990.<br />

data otrzymania pracy: 27.09.2010 r.<br />

data akceptacji do druku: 28.10.2010 r.<br />

Adres do korespondencji:<br />

Marcin T. Nowak<br />

ul. Wyspiańskiego 21<br />

43-300 Bielsko-Biała<br />

Tel. +48 602 558-301<br />

e-mail: info@proktomed.pl<br />

13

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