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Životné podmienky a zdravie 2003

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indirect energometric point at two basic factors informing us about metabolic state of<br />

organism:<br />

a) RQ – represent factual proportion of utilised substrate – so called metabolic level that is<br />

present utilisation of sustenance.<br />

b) We can also observe utilisation reverse in particular level that is haw is the organism able<br />

to energetic utilise certain proportion of sustenance – metabolic reverse. With the help of<br />

indirect energometric we can not only evaluate individual dietetic covering of physical<br />

activity, but to evaluate the proportion of individual sustenance for covering sport<br />

performance as well. In case of specific situations Bergman´s minimal model of kinetics<br />

can be employed to reach higher accuracy.<br />

In practical use we employ methods of indirect energometric for evaluation of basic energy<br />

output with the help of Daltatrac – Datex, Sport 2000 or Infralyt instruments. Acquired<br />

parameters are correlated with anthropometrical and biochemical indexes. The method<br />

enables immediate detection of the state of energy in organism and thus makes possible to<br />

determine appropriate diet intervention. In selected observations we also practise long-term<br />

evaluation of absorbing of individual part of nutrition during oral glucose or lipid test with the<br />

detection of the effect on organism energy and individual supporting departments. Acquired<br />

rates present a base for application of individual dieted steps to secure extreme metabolic<br />

situations. It also enables us to predict the development of energy balance of organism.<br />

Typical rundown is according to particular kind of sport. Acquired rates of indirect<br />

energometric point at two basic factors informing us about metabolic state of organism:<br />

c) RQ – represent factual proportion of utilised substrate – so called metabolic level that is<br />

present utilisation of sustenance.<br />

d) We can also observe utilisation reverse in particular level that is haw is the organism able<br />

to energetic utilise certain proportion of sustenance – metabolic reverse. With the help of<br />

indirect energometric we cannot only evaluate individual dietetic covering of physical<br />

activity, but to evaluate the proportion of individual sustenance for covering sport<br />

performance as well. In case of specific situations Bergman´s minimal model of kinetics<br />

can be employed to reach higher accuracy.<br />

REFERENCE:<br />

1. Zinn, A. B., Kerr, D. S. and Hoppel, C. L.: Fumarase deficiency: a new cause of mitochondrial<br />

encephalomyopathy. N Engl J Med, 315, 1986, s. 469-475.<br />

2. Hoppel, C. L., Kerr ,D. S., Dahms, B. and Roessmann, U.: Deficiency of the reduced nicotinamide adenine<br />

dinucleotide dehydrogenase component of complex I of mitochondrial electron transport. Fatal infantile<br />

lactic acidosis and hypermetabolism with skeletal-cardiac myopathy and encephalopathy. J Clin Invest, 80,<br />

1987, s. 71-77.<br />

3. Kerr, D. S., Ho, L., Berlin, C. M., Lanoue, K. F., Towfighi, J., Hoppel, C. L., Lusk, M. M., Gondek, C. M.<br />

and Patel, M. S.: Systemic deficiency of the first component of the pyruvate dehydrogenase complex.<br />

Pediatr Res., 22, 1987, s. 312-318.<br />

4. Ross, N. S. and Hoppel, C. L.: Partial muscle carnitine palmitoyltransferase-A deficiency. J Am Med<br />

Assoc., 257, 1987, s. 62-65.<br />

5. Tserng, K. Y., Jin, S. J., Kerr, D. S. and Hoppel, C. L.: Urinary 3-hydroxydicarboxylic acids in the<br />

pathophysiology of metabolic disorders with dicarboxylic aciduria. Metabolism, 40, 1991, s. 676-682.<br />

6. Kerr, D. S.: Lactic acidosis and mitochondrial disorders. Clin Biochem., 24, 1992, s. 331-336.<br />

7. Minkler, P. E. and Hoppel, C. L.: Quantification of free carnitine, individual short- and medium-chain<br />

acylcarnitines, and total carnitine in plasma by high-performance liquid chromatography. Anal Biochem.,<br />

212, 1993, s. 510-518.<br />

8. Minkler, P. E. and Hoppel, C. L.: Quantification of carnitine and specific acylcarnitines by highperformance<br />

liquid chromatography: application to normal human urine and urine from patients with<br />

methylmalonic aciduria, isovaleric acidemia or medium-chain acyl-CoA dehydrogenase deficiency. J<br />

Chromatogr., 613, 1993, s. 203-221.<br />

293

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