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Seroprevalencija i faktori rizika za infekciju virusom hepatitisa C u ...

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were associated with HCV seropositivity. The prior HBV infection (p=0.002) and<br />

gonorrhea (p=0.011) were the only risk factors significantly associated with anti-<br />

HCV prevalence. No other factors reflecting risk sexual behavior such as sexual<br />

orientation (p=0.355), the number of sexual partners (p=0.318) and the number of<br />

risk factors (p=0.079) were associated with HCV seroprevalence. HCV-RNA was<br />

detected in 73.1% seropositive participants. Three of the seronegative cases<br />

(2.1%) were also found to be HCV-RNA positive (“window period”). The majority of<br />

participants were infected with genotype 1 (55.6%), 38.9% with genotype 3 and<br />

5.6% with genotype 4. The most prevalent subtypes were 1a (38.9%) and 3a<br />

(38.9%). According to the risk groups, in persons with multiple sexual partners all<br />

three genotypes (subtypes 1a and 3a) were detected. MSM were infected with<br />

genotypes 3a and 4, CSW and their clients with genotypes 1a and 3a and persons<br />

with STDs were infected with genotypes 1 (subtypes 1a and 1b) and 3a.<br />

101

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