Seroprevalencija i faktori rizika za infekciju virusom hepatitisa C u ...

8. SUMMARY
We analyzed the seroprevalence, genotypes and risk factors for HCV infection in
groups with high-risk sexual behavior: persons with multiple sexual partners, men
who have sex with men (MSM), commercial sex workers and their clients (CSW)
and persons with sexually transmitted diseases (STDs). Control group consisted of
pregnant females. A total of 821 patients were enrolled in the study: 716 (87.2%)
males and 105 (12.8%) females. The mean age was 35.8+11.5 years. Median age
was 32 years (range 18-77 years). Seventy-one point five percent of participants
reported one risk sexual behavior, 25.2% reported two, 3.2% reported three and
0.1% of participants reported four risk sexual behaviors. Median number of sexual
partner in the preceding year was 2 (range 0-100). A prior history of STDs had
25.3% participants. Hepatitis B virus (HBV) infection was the most frequently
reported (12.8%) followed by gonorrhea (4.6%), C. trachomatis (2.7%) and HPV
infection (2.7%), genital/anal herpes (1.6%) and syphilis (1.0%). The overall HCV
seroprevalence was 4.6%: 6.3% in persons with multiple sexual partners, 2.9% in
MSM, 4.0% in CSW and their clients and 8.5% in persons with STDs compared to
0.5% in control group. HCV seroprevalence was significantly higher than in
controls in all risk groups except MSM [persons with multiple sexual partners:
OR=13.49; 95% CI (OR)=1.81-100.4; CSW and their clients: OR=8.39; 95% CI
(OR)=1.07-65.5; persons with STDs: OR=18.59; 95% CI (OR)=2.4-141.1; MSM
OR=6.00; 95% CI (OR)=0.72-50.2]. The difference of HCV seroprevalence
between age groups was not statistically significant (p=0.230). The highest
seroprevalence was reported in the 20-29 age group (5.8%) and in the 30-39 age
group (5.7%). Neither marital status (p=0.681) nor level of education (p=0.978)
100