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iv‹çindekilerPlazma Proteinlerine Ba¤lanma ............................................................. 31‹laçlar›n Da¤›l›m H›z›n› De¤ifltiren Etkenler.......................................... 31‹yon Tuza¤›.............................................................................................. 31Redistribüsyon ......................................................................................... 32Sekestrasyon ............................................................................................ 32‹laçlar›n Da¤›l›m›n› S›n›rlayan Fizyolojik Engeller ................................ 32‹laçlar›n Eliminasyonu................................................................................... 32Biyotransformasyon................................................................................. 33Biyotransformasyonda Rol Oynayan Enzimatik Olaylar....................... 33At›l›m........................................................................................................ 35FARMAKOD‹NAM‹ ........................................................................................ 37Terapötik Pencere ......................................................................................... 37‹laçlar›n Etki Mekanizmalar› ......................................................................... 37‹laç Etkisini De¤ifltiren Etkenler ................................................................... 41Özet ............................................................................................................... 43Kendimizi S›nayal›m ..................................................................................... 45Kendimizi S›nayal›m Yan›t Anahtar› ............................................................ 46S›ra Sizde Yan›t Anahtar› .............................................................................. 47Kaynaklar....................................................................................................... 473. ÜN‹TE‹laç Etken Maddeleri................................................................ 48G‹R‹fi .............................................................................................................. 49AR‹LALK‹LAM‹N TÜREVLER‹........................................................................ 50Ariletilamin Türevleri .................................................................................... 50Arilpropilamin Türevleri ............................................................................... 51Arilbütilamin Türevleri .................................................................................. 54AM‹NOALKOL ESTERLER‹............................................................................ 54Aminoalkol Ester Türevi Lokal Anastezikler ............................................... 56AR‹LALKANO‹K AS‹T TÜREV‹ B‹LEfi‹KLER................................................. 57SAL‹S‹L‹K AS‹T VE ANTRAN‹L‹K AS‹T TÜREV‹ ANALJEZ‹KLER ............... 59PROPAND‹OL TÜREV‹ M‹YORÖLAKSANLAR............................................. 60PROPANOLAM‹N TÜREV‹ ANT‹H‹PERTANS‹F ‹LAÇLAR ........................... 61SÜLFONAM‹T TÜREVLER‹............................................................................ 61Sülfanilamit Türevleri Antibakteriyeller........................................................ 61Aril Sülfonamit Türevi Diüretikler................................................................ 62Sülfonilüre Türevi Hipoglisemiyanlar .......................................................... 64ÜRE, AÇ‹LÜRE VE KARBAMAT B‹LEfi‹KLER‹.............................................. 64Barbitürik Asit Türevleri................................................................................ 66Hidantoinler................................................................................................... 67Süksinimit Türevleri ...................................................................................... 67BENZOD‹AZEP‹N TÜREVLER‹ ..................................................................... 68TR‹S‹KL‹K NÖROLEPT‹KLER VE ANT‹DEPRESANLAR............................... 70Fenotiyazin Türevi Nöroleptikler ................................................................. 70Tiyoksanten Türevi Nöroleptikler ................................................................ 71Trisiklik Antidepresanlar............................................................................... 71D‹H‹DROP‹R‹D‹N TÜREV‹ ANT‹H‹PERTANS‹F ‹LAÇLAR .......................... 72N‹TROHETEROS‹KL‹K ANT‹BAKTER‹YEL B‹LEfi‹KLER ............................. 73Nitrofuranlar .................................................................................................. 73Nitroimidazol Türevleri ................................................................................. 73Nitrotiyazol Türevleri .................................................................................... 74
‹çindekilervK‹NOLON GRUBU ANT‹B‹YOT‹KLER......................................................... 74AZOL GRUBU ANT‹FUNGALLER................................................................. 75Azol Türevleri................................................................................................ 75β-LAKTAM ANT‹B‹YOT‹KLER ...................................................................... 76Penisilin ve Sefalosporin Türevi Antibiyotikler ........................................... 76Sefalosporinler............................................................................................... 78Özet................................................................................................................ 79Kendimizi S›nayal›m...................................................................................... 80Kendimizi S›nayal›m Yan›t Anahtar› ............................................................ 81Kaynaklar....................................................................................................... 81‹laçlar›n Kullan›m Alanlar›.........................................................82G‹R‹fi .............................................................................................................. 83KALP VE DAMAR S‹STEM‹ HASTALIKLARININ TEDAV‹S‹NDEKULLANILAN ‹LAÇLAR ................................................................................. 83Hipertansiyon Tedavisinde Kullan›lan ‹laçlar.............................................. 83Hipotansiyon Tedavisinde Kullan›lan ‹laçlar............................................... 84Anjina Pektoris Tedavisinde Kullan›lan ‹laçlar............................................ 84Aritmi Tedavisinde Kullan›lan ‹laçlar........................................................... 84Kalp Yetmezli¤inin Tedavisinde Kullan›lan ‹laçlar ..................................... 84Periferik Arter Hastal›klar›n›n Tedavisinde Kullan›lan ‹laçlar..................... 85Hiperlipidemi Tedavisinde Kullan›lan ‹laçlar .............................................. 85SOLUNUM S‹STEM‹ HASTALIKLARININ TEDAV‹S‹NDEKULLANILAN ‹LAÇLAR ................................................................................. 85S‹ND‹R‹M S‹STEM‹ HASTALIKLARININ TEDAV‹S‹NDEKULLANILAN ‹LAÇLAR ................................................................................. 86Gastrit, Ülser ve Reflü Tedavisinde Kullan›lan ‹laçlar ................................ 86Laksatif ve Purgatif ‹laçlar ............................................................................ 86Hemoroit Tedavisinde Kullan›lan ‹laçlar ..................................................... 86Diyare Tedavisinde Kullan›lan ‹laçlar .......................................................... 87Antiemetik ve Emetik ‹laçlar ........................................................................ 87Sindirim Sistemi Hastal›klar›n›n Tedavisinde Kullan›lanDi¤er ‹laçlar .................................................................................................. 87GEN‹TOÜR‹NER S‹STEM HASTALIKLARININTEDAV‹S‹NDE KULLANILAN ‹LAÇLAR........................................................ 88KAN HASTALIKLARININ TEDAV‹S‹NDE KULLANILAN ‹LAÇLAR.............. 89PS‹K‹YATR‹K VE NÖROLOJ‹K S‹STEM HASTALIKLARINTEDAV‹S‹NDE KULLANILAN ‹LAÇLAR........................................................ 90Duygudurum ve Anksiyete Bozukluklar›n›n TedavilerindeKullan›lan ‹laçlar ........................................................................................... 90Psikotik Bozukluklar›n Tedavisinde Kullan›lan ‹laçlar ............................... 90Uyku Bozukluklar›n›n Tedavisinde Kullan›lan ‹laçlar ................................ 90Epilepsi Tedavisinde Kullan›lan ‹laçlar........................................................ 90Parkinson Hastal›¤›n›n Tedavisinde Kullan›lan ‹laçlar................................ 91Alzheimer Hastal›¤› ve Demans Tedavisinde Kullan›lan ‹laçlar................. 91ENDOKR‹N S‹STEM HASTALIKLARININ TEDAV‹S‹NDEKULLANILAN ‹LAÇLAR ................................................................................. 91Diabetes mellitus Tedavisinde Kullan›lan ‹laçlar ........................................ 91Tiroit Bezi ‹fllev Bozukluklar›nda Kullan›lan ‹laçlar ................................... 92Kortikosteroitler............................................................................................. 934. ÜN‹TE
Page 1: ‹çindekileriii‹çindekilerÖns
Page 5 and 6: ‹çindekilerviiKendimizi S›naya
Page 7 and 8: ‹çindekilerixÖzet .............
Page 9 and 10: ‹çindekilerxiParçalanm›fl vey
Page 11 and 12: ÖnsözxiiiBu kitab›n haz›rlama
Page 13 and 14: ‹lac›n Keflfi ve Tarihçesi‹L
Page 15 and 16: 1. Ünite - ‹lac›n Keflfi ve Ta
Page 17 and 18: 71. Ünite - ‹lac›n Keflfi ve T
Page 29 and 30: Genel ‹laç BilgisiG‹R‹fiBu
Page 31 and 32: SORUS ORUD ‹KKATD‹KKAT2. SIRA
Page 33 and 34: 2. Ünite - Genel ‹laç Bilgisi23
Page 39 and 40: 2. Ünite - Genel ‹laç Bilgisiru
Page 41 and 42: SIRA S‹ZDESIRA S‹ZDEDÜfiÜNEL
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2. Ünite - Genel ‹laç Bilgisi43
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‹laç Etken MaddeleriG‹R‹fi
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3. Ünite - ‹laç Etken Maddeleri
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‹laçlar›n Kullan›m Alanlar
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4. Ünite - ‹laçlar›n Kullan
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‹laçlar›n ‹stenmeyen Etkiler
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5. Ünite - ‹laçlar›n ‹stenm
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D‹KKATD‹KKAT5. Ünite - ‹laç
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6PRAT‹K ‹LAÇ B‹LG‹S‹,
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140 Pratik ‹laç Bilgisi, ‹laç
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‹laçlar›n Saklama Koflullar›
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9. Ünite - ‹laçlar›n Saklama
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Pratik Müstahzar BilgisiG‹R‹fi
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• Ofisinal ilaçlar,• Majistral
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10. Ünite - Pratik Müstahzar Bilg
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D‹KKATD‹KKATSIRA S‹ZDESIRA S
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DÜfiÜNEL‹MDÜfiÜNEL‹MSORUS O
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‹laç D›fl› ÜrünlerG‹R‹
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SIRA S‹ZDESIRA S‹ZDE11. Ünite
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11. Ünite - ‹laç D›fl› Ür
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S ORUSORUD‹KKAT11. Ünite - ‹la
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PRAT‹K ‹LAÇ B‹LG‹S‹, ‹
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SIRA S‹ZDEDÜfiÜNEL‹MSIRA S‹
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