akne vulgarisin topikal tedavisinde tretinoin, eritromisin ve tretinoin + ...

More documents

Recommendations

Info

THE EFFICACY OF TRETINOIN, ERYTROMYCIN AND TRETINOIN+ERYTROMYCIN IN THE TOPICAL TREATMENT OF ACNE VULGARIS SUMMARY Acne vulgaris is a chronic inflammatory disease of the pilosebaseous follicles, characterized by polimorphous lesions like papules, pustules, nodules and often scars and it affects sebaseous regions like face, neck, upper trunk. There are lots of topical and systemic agents used in the treatment of acne vulgaris; like keratolitics, antiinflammatory agents, antibacterials and agents which reduce sebum secretion. We compared the effectiveness and side effects (erytema, kserosis and burning) of tretinoin 0.05% cream and erythromycin 4% gel when used in treatment of acne vulgaris separetely and together. We separete 150 patients with mild and moderate acne vulgaris into three randomized groups and treated one group with combination of this two for eight weeks. In the beginning, we count the lesions of patiens in two groups as inflammatory and noninflammatory and we repeat the same procedure secondary, fourth and eighth weeks and we observed the side effects. At the end of eighth week, tretinoin was more effective to noninflammatory lesions, erythromycin was more effective to inflammatory lesions. There was statistycally important differance effectiveness and side effects of these between two agents but all of acne vulgaris. 48
We determined that both tretinoin and erytromycin were effective and tolerable agents in acne vulgaris; the usage of combination of then was not more effective than the usage of any of these agents on one’s own. Tretinoin and erytromycin combination caused more side effects than the erytromycin alone. Key words: Acne vulgaris, tretinoin, erytromycin 49
Page 1 and 2: T.C. TRAKYA ÜNİVERSİTESİ TIP FA
Page 3 and 4: İÇİNDEKİLER GİRİŞ VE AMAÇ .
Page 5 and 6: GİRİŞ VE AMAÇ Akne vulgaris, pi
Page 7 and 8: ETYOLOJİ VE PATOGENEZ Akne vulgari
Page 9 and 10: Normal bir follikülde keratinositl
Page 11 and 12: sitokinlerle devam eder. Akne vulga
Page 13 and 14: DERECELENDİRME Akne hastasında uy
Page 15 and 16: ulunmuştur (50). Ayrıca yapılan
Page 17 and 18: Tablo 2. Akneiform lezyonlara yol a
Page 19 and 20: Tablo 3. Akne tedavisinde kullanıl
Page 21 and 22: e) Retinaldehit: Keratinositlerdeki
Page 23 and 24: deri florasında değişiklik ve di
Page 25 and 26: iyolojik olarak aktif androjenleri
Page 27 and 28: soruldu. Bu bulgular yok=0, hafif=1
Page 29 and 30: Hastalık süresi medyanı, çalı
Page 31 and 32: Tablo 8. T grubunda tedavi süresin
Page 33 and 34: istatistiksel olarak anlamlı orand
Page 35 and 36: Hasta Sayısı 45 40 35 30 25 20 15
Page 41 and 42: Şekil 18 ve 19’da eritromisin %4
Page 43 and 44: Şekil 22 ve 23’te eritromisin+tr
Page 45 and 46: Bernstein ve Shalita (15), 348 hast
Page 47 and 48: tüm lezyonlar üzerine etkisi, pla
Page 49 and 50: eritromisin+%0.025 tretinoin kombin
Page 51: ÖZET Akne vulgaris, yüz, sırt, g
Page 55 and 56: 11. Cunliffe WJ, Holland DB, Jeremy
Page 57 and 58: 45. Witkowski JA, Parish LC. The as
Page 59 and 60: EKLER 55
Page 61 and 62: EK 2 BİLGİLENDİRİLMİŞ OLUR FO
Page 63 and 64: Olgu No: Prot. No: İsim: Yaş: Cin
Page 65: EK 4 Hastaların Demografik Özelli

akne vulgarisin topikal tedavisinde tretinoin, eritromisin ve tretinoin + ...

Create successful ePaper yourself

Delete template?

Save as template?