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Ryg sektionen, Ortopedkliniken Ryggsektionen, Ortopedkliniken ...

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Lumbala diskbråck<br />

Jan Willén<br />

bättre, men operationstiden längre,<br />

blödningen inte mindre och<br />

sjukskrivningstiden inte kortare än vid<br />

öppen kirurgi (Tullberg et al, 1993,<br />

Henriksen et al, 1996, Lagarrigue et al,<br />

1994).<br />

Nukleotomi: Endast 10-15 % av de patienter,<br />

som opererades med nukleotomi var aktuella<br />

för öppen kir. Men då var resultaten<br />

liknande de i Webers konservativa grupp<br />

(Mayer et al, 1993). Laserkirurgi: Ingen<br />

acceptabel evidence (Gibson et al, 1999).<br />

Komplikationer: Postoperativ<br />

komplikationsfrekvens är signifikant<br />

korrelerad till förekomst av fetma,<br />

hypertension och diabetes.<br />

Typ av komplikationer: Spondylodiscit utan<br />

peroperativ antibiotikabehandling är 3-4 %<br />

(Petri et al, 1996, Rohde et al, 1998)<br />

Tromboflebiter 0,3 ‰. Mortalitet 0,9 ‰.<br />

Total cauda equina frekvens 5 ‰<br />

(Henriques, 2001). Total<br />

komplikationsfrekvens 3.7 % (Kardaun et al,<br />

1990).<br />

Referenser :<br />

van Alphen HA, Braakman R, Bezemer PD et al.<br />

Chemonucleolysis versus discectomy: a randomized<br />

multicenter trial. J Neurosurg 1989;70(6):869-75.<br />

Crawshaw C, Frazer AM, Merriam WF et al. A<br />

comparison of surgery and chemonucleolysis in the<br />

treatment of sciatica. A prospective randomized trial.<br />

Spine 1984;9(2):195-8.<br />

Dabezies EJ, Langford K, Morris J et al. Safety<br />

and efficacy of chymopapain (Discase) in the<br />

treatment of sciatica due to a herniated nucleus<br />

pulposus: Results of a reandomized, double-blind<br />

study. Spine 1988;13:561-5.<br />

Feldman J, Menkes CJ, Pallardy G et al. Doubleblind<br />

study of the treatment of disc lumbosciatica by<br />

chemonucleolysis. Rev Rhum Mal Osteoartic<br />

1986;53(3):147-52.<br />

Fraser RD. Chymopapain for the treatment of<br />

intervertebral disc hernication. A preliminary report<br />

of a double-blind study. Spine 1982;7(6):608-12.<br />

Gibson JN, Grant IC, Waddell G. Cochrane<br />

Review of surgery for lumbar disc prolapse and<br />

degenerative lumbar spondylosis. Spine<br />

1999;24(17):1820-32.<br />

14<br />

Henriksen L, Schmidt K, Eskesen V et al. A<br />

controlled study of microsurgical versus standard<br />

lumbar discectomy. Br J Neurosurg 1996;10(3):289-<br />

93.<br />

Henriques T, Olerud C,, Petrén-Mallmin M et al.<br />

Cauda equina syndrome as a postoperative<br />

complication in five patients operated for lumbar disc<br />

herniation. Spine 2001;26(3):2404-5.<br />

Hoffman RM, Wheeler KJ, Deyo RA. Surgery for<br />

herniated lumbar discs: A literature synthesis. J Gen<br />

Intern Med 1993;8:487-96.<br />

Javid MJ, Nordby EJ, Ford LT et al. Safety and<br />

efficacy of chymopapain (Chymodiactin) in herniated<br />

nucleus pulposus with sciatica. Results of a<br />

randomized, double-blind study. JAMA<br />

1983;249(18):2489-94.<br />

Kardaun JW, White LR, Shaffer WO. Acute<br />

complications in patients with surgical treatment of<br />

lumbar herniated disc. J Spinal Disord 1990;3(1):30-8.<br />

Lagarrigue J, Chaynes P. Comparative study of<br />

disk surgery with or without microscopy. A<br />

prospective study of 80 cases. Neurochirurgie<br />

1994;40(2):116-20.<br />

Lavignolle B, Vital JM, Baulny D et al.<br />

Comparative study of surgery and chemonucleolysis<br />

in the treatment of sciatica caused by a herniated disk.<br />

Acta Orthop Belg 1987;53(2):244-9.<br />

Mayer HM, Brock M. Percutaneous endoscopic<br />

discectomy: surgical technique and preliminary results<br />

compared to microsurgical discectomy. J Neurosurg<br />

1993;78(2):216-25.<br />

Petri A, Jensen IP. Postoperative lumbar discitis.<br />

Types, diagnosis and treatment. Ugeskr Laeger<br />

1996;158(38):5281-5.<br />

Rohde V, Meyer B, Schaller C et al.<br />

Spondylodiscitis after lumbar discectomy. Incidence<br />

and a proposal for prophylaxis. Spine 1998;23(5):615-<br />

20.<br />

Tullberg T, Isacson J, Weidenhielm L. Does<br />

microscopic removal of lumbar disc herniation lead<br />

to better resuts than the standard procedure? Results<br />

of a one-year randomized study. Spine 1993;18(1):24-<br />

7.<br />

Vucetic N, de Bri E, Svensson O. Clinical history<br />

in lumbar disc herniation. A prospective study in 160<br />

patients. Acta Orthop Scand 1997;68(2):116-20.<br />

Weber H. Lumbar disc herniation: A prospective<br />

study of prognostic factors including a controlled<br />

trial. University of Oslo, MD Thesis, 1978.<br />

Weber H. Lumbar disc herniation: A controlled,<br />

prospective study with ten years of observation. Spine<br />

1983;8:131-40.

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