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2011, nr. 1 - Academia de Ştiinţe a Moldovei

2011, nr. 1 - Academia de Ştiinţe a Moldovei

2011, nr. 1 - Academia de Ştiinţe a Moldovei

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<strong>Ştiinţe</strong> Medicale<br />

Bibliografi e<br />

1. Beletsky V., Nadareishvili Z., Lynch J., Shuaib A.,<br />

Woolfen<strong>de</strong>n A., Norris J.W.<br />

Cervical arterial dissection: time for a therapeutic trial?<br />

Stroke, <strong>de</strong>c. 2003; 34(12):2856-2860.<br />

2. Norris J.W., Beletsky V. Sud<strong>de</strong>n neck movement<br />

and cervical artery dissection. Th e Canadian Stroke Consortium.<br />

CMAJ, july, 11 2000; 163(1):38-40.<br />

3. Rubinstein S.M., Peer<strong>de</strong>man S.M, van Tul<strong>de</strong>r<br />

M.W. A systematic review of the risk factors for cervical artery<br />

dissection. Stroke, july 2005; 36(7): 1575 – 1580.<br />

4. Saeed A.B., Shuaib A., Al-Sulaiti G. Vertebral artery<br />

dissection: warning symptoms, clinical features and<br />

prognosis in 26 patients. Can. J. Neurol. Sci., nov. 2000;<br />

27(4):292-296.<br />

5. Gonzales-Portillo F., Bruno A., Biller J. Outcome<br />

of extracranial cervicocephalic arterial dissections: A follow-up<br />

study. Neurol. Res., 2002; 24(4):395-398.<br />

6. Caplan L.R., Zarins C.K., Hemmati M. Spontaneous<br />

dissection of the extracranial vertebral arteries. Stroke,<br />

1985; 16:1030-1037.<br />

7. Lee V.H., Brown R.D., Mandrekar J.N., Mokri B.<br />

Inci<strong>de</strong>nce and outcome of cervical artery dissection: a population-based<br />

study. Neurology, 2006; 67: 1809–1812.<br />

8. Kim Y.K., Schulman S. Cervical artery dissection:<br />

pathology, epi<strong>de</strong>miology and management. Th romb. Res.,<br />

(april, 2009, 123 (6): 810–821.<br />

9. Campos-Herrera C.R., Scaff M., Yamamoto F.I.,<br />

Conforto A.B. Spontaneous cervical artery dissection: an update<br />

on clinical and diagnostic aspects. Arq. Neuropsiquiatr,<br />

2008, 66 (4): 922–927.<br />

10. Debette S., Markus H.S. Th e genetics of cervical artery<br />

dissection: a systematic review. Stroke, june, 2009, 40<br />

(6): e459–466.<br />

11. Debette S., Leys D. Cervical-artery dissections: predisposing<br />

factors, diagnosis, and outcome. Lancet, Neurol., 8<br />

july 2009, 7: 668–678.<br />

12. Arnold M., Bousser M.G. Clinical manifestations<br />

of vertebral artery dissection. Front. Neurol. Neurosci, 2005;<br />

20: 77-86.<br />

13. Provenzale J.M., Sarikaya B. Comparison of test<br />

performance characteristics of MRI, MR angiography, and<br />

CT angiography in the diagnosis of carotid and vertebral<br />

artery dissection: a review of the medical literature. Am. J.<br />

Roentgenol October, 2009, 193 (4): 1167–774.<br />

Rezumat<br />

Disecţia arterei vertebrale este o cauză importantă a<br />

acci<strong>de</strong>ntului vascular cerebral la pacienţii tineri. Aceasta<br />

poate fi spontană sau traumatică și poate conduce la diferite<br />

simptome clinice.<br />

Am <strong>de</strong>scris un caz clinic, al pacientului C. <strong>de</strong> 38 <strong>de</strong><br />

ani, care nu a suportat recent o traumă sau alt eveniment<br />

<strong>de</strong>clanșator, <strong>de</strong>butul maladiei fi ind acut cu <strong>de</strong>zechilibru,<br />

dizartrie, disfagie, parestezii în hemicorpul stâng, cefalee și<br />

dismetrie. Examenul medical a obiectivizat disecția arterei<br />

vertebrale drepte, AVC ischemic în sistemul vertebrobazilar,<br />

sindrom bulbar, hemipareză pe dreapta și tulburări cerebeloase.<br />

29<br />

Summary<br />

Vertebral Artery Dissection in Young Adults – Case<br />

Report and Review of the Literature Vertebral artery dissection<br />

is a important cause of stroke in young patients. It<br />

may be spontaneous or traumatic and can lead to various<br />

clinical symptoms.<br />

We <strong>de</strong>scribe a case of 38-year-old man, with no preceding<br />

trauma or apparent inciting event, presented with the<br />

acute onset of imbalance, dysarthria, left -si<strong>de</strong>d paresthesias,<br />

headache, dysphagia, and dysmetria. Workup revealed<br />

a right vertebral artery dissection, ischemic stroke in the<br />

vertebro-basilar system, bulbar syndrome, right hemiparesis<br />

and cerebellar disor<strong>de</strong>rs.<br />

Pезюме<br />

Диссекция позвоночной артерии является важной<br />

причиной нарушения мозгового кровообращения<br />

(инсульта) у молодых пациентов. Она может быть<br />

спонтанной или травматической, и приводят к разным<br />

клиническим симптомам.<br />

Описан клинический случай пациента К., 38 лет,<br />

который не перенес недавно травму и не имел другой<br />

какой-либо провоцирующий фактор. Начало заболевания<br />

проявилось остро нарушением равновесия, дизартрией,<br />

дисфагией, парестезиями в левой половине<br />

тела, головной болью и дисметрией. Медицинские обследования<br />

объектизировали диссекцию правой вертебральной<br />

артерии, ОНМК (ишемический инсульт)<br />

в вертебро-базилярном бассейне, бульбарные нарушения,<br />

правосторонний гемипарез и мозжечковые расстройства.<br />

REZULTATELE TESTULUI<br />

CU ÎNCLINARE LA PACIENŢII<br />

CU MIGRENĂ ASOCIATĂ CU SINCOPĂ<br />

_______________________________________<br />

Galina Corcea, medic-neurolog,<br />

IMSP Institutul <strong>de</strong> Neurologie și<br />

Neurochirurugie<br />

Introducere. Migrena ca entitate nozologică este<br />

inclusă în grupa cefaleelor primare, având ca substrat<br />

patogenic fundamental fenomenul <strong>de</strong> activare trigeminovasculară.<br />

Totuși, rezultatele cercetărilor privind<br />

mecanismele patogenice ale migrenei sunt controversate.<br />

Multe dintre simptomele ce însoţesc atacul migrenos<br />

sau pot apărea și interictal (fotofobie, greţuri,<br />

vome sau disfuncţie gastrochinetică, variaţii ale TA,<br />

palpitaţii cardiace, transpiraţie, piloerecţie, micţiuni<br />

frecvente ș.a.) sunt <strong>de</strong> geneză vegetativă sugerând implicarea<br />

Sistemului Nervos Autonom (SNA) în meca-

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