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• Studiile au arătat că cele două bariere se<br />

comportă cel mai adesea ca membrane lipidice.<br />

• Astfel, medicamentele admin<strong>is</strong>trate intravenos<br />

trec în creier sau L.C.R. la rate proportionale cu<br />

coeficientul lor de partaj si constanta de<br />

d<strong>is</strong>ociatie, la pH 7,4.<br />

• Printre barierele sânge - creier si sânge - L.C.R.<br />

trec o serie de medicamente: cloroform, eter,<br />

halotan, cloral hidrat, barbiturice s.a.

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