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Identificarea profilelor moleculare transcriptomice in cancerul de col ...

Identificarea profilelor moleculare transcriptomice in cancerul de col ...

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Activitati prevazute pt 2011:Perspective 2011Realizarea studiului <strong>de</strong> genomica (hibridarea son<strong>de</strong>lor microarray pelame WHG (4x44k); validarea rezultatelor microarray pr<strong>in</strong> qRT-PCR;corelarea datelor <strong>de</strong> genomica cu subtipul viral HPV si raspunsul laterapie;Obiectivele preconizate a fi at<strong>in</strong>se:Realizarea unui mo<strong>de</strong>l experimental, bazat pe studii <strong>de</strong> genomicafunctionala si genotipare HPV, ca factor <strong>de</strong> predictie <strong>in</strong> raspunsul laradio- chimioterapie <strong>in</strong> <strong>cancerul</strong> <strong>de</strong> <strong>col</strong> uter<strong>in</strong> (IIB-IIIB).Elemente <strong>de</strong> orig<strong>in</strong>alitate:Comb<strong>in</strong>area analizei <strong>transcriptomice</strong> cu genotiparea HPV (37 subtipuri)Necesar f<strong>in</strong>antare pt 2011:Ramas d<strong>in</strong> contractare: 1.533.355 leiAt<strong>in</strong>gerea obiectivelor propuse <strong>in</strong>itial: 650.000-700.000 lei

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