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Identificarea profilelor moleculare transcriptomice in cancerul de col ...

Identificarea profilelor moleculare transcriptomice in cancerul de col ...

Identificarea profilelor moleculare transcriptomice in cancerul de col ...

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Obiectiv: Realizarea unui mo<strong>de</strong>l experimental, bazat pe studii <strong>de</strong> genomicafunctionala si genotipare HPV, ca factor <strong>de</strong> predictie <strong>in</strong> raspunsul la radiochimioterapie<strong>in</strong> <strong>cancerul</strong> <strong>de</strong> <strong>col</strong> uter<strong>in</strong> (IIB-IIIB).Rezultatul f<strong>in</strong>al al proiectului: O metoda moleculara <strong>de</strong> <strong>in</strong>vestigatie <strong>in</strong>medic<strong>in</strong>a pentru predictia la terapie <strong>in</strong> <strong>cancerul</strong> <strong>de</strong> <strong>col</strong> uter<strong>in</strong>.Elemente <strong>de</strong> noutate:Stabilirea unei semnaturi <strong>moleculare</strong> <strong>transcriptomice</strong> la nivelul <strong>in</strong>treguluigenom uman ca predictie a raspunsului la terapie functie <strong>de</strong> <strong>in</strong>carcaturavirala HPV.Orig<strong>in</strong>alitate:Comb<strong>in</strong>area analizei <strong>transcriptomice</strong> cu genotiparea HPV (37 subtipuri)Beneficiarii rezulatelor, potentialul <strong>de</strong> aplicare <strong>in</strong> economie• bolnavii on<strong>col</strong>ogi care pot beneficia <strong>de</strong> un tratament <strong>in</strong>dividualizat;• sistemul <strong>de</strong> sanatate pr<strong>in</strong> costurilor legate <strong>de</strong> eficientizarea tratamenteloron<strong>col</strong>ogice;• t<strong>in</strong>erii doctoranzi –specializare <strong>in</strong> domenii <strong>de</strong> varf – genomica• comunitatea sti<strong>in</strong>tifica <strong>in</strong>ternationala pr<strong>in</strong> prezentarea datelor obt<strong>in</strong>ute <strong>in</strong>urma studiului <strong>de</strong> cerectare.• companii farmaceutice <strong>in</strong>teresate sa utilizeze <strong>in</strong>formatiile genomice pentrustabilirea <strong>de</strong> teste <strong>de</strong> predictie si <strong>de</strong> medicamente mai eficiente.

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