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curs sedative, timostabilizatori si medicatia in demente - Psihiatrie ...

curs sedative, timostabilizatori si medicatia in demente - Psihiatrie ...

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Hipnoticele moderne:<br />

zopiclone şi zolpidem<br />

• Risc de dependenţă redus<br />

• Efect scurt: 7 ore<br />

• Trezire nocturnă după încetarea efectului<br />

• Zolpidem:<br />

– 10 mg/zi<br />

– Absorbţie redusă de alimente<br />

– Sertral<strong>in</strong>a poate creşte concentraţia plasmatică a zolpidemului<br />

– T1/2: 2,5h<br />

• Zopiclone:<br />

– 7,5 mg/zi<br />

– Fluvoxam<strong>in</strong>a poate cereşte concentraţia plasmatică a zopiclonei<br />

– T1/2: 3,5-6,5h<br />

– Supradozaj cu potenţial fatal

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