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Jurnalul Român <strong>de</strong> Psih<strong>of</strong>armacologie<br />

Romanian Journal <strong>of</strong> Psychopharmacology<br />

Vol. 6, Nr. 1, 2<br />

ANTIPSIHOTICELE DE A II-A GENERAŢIE<br />

ÎN TRATAMENTUL TULBURĂRILOR DE CONVERSIE<br />

A. Tiugan, Claudia Răduţ<br />

Spitalul Clinic <strong>de</strong> Urgenţă Militar „Dr. Ştefan.Odobleja” Craiova<br />

Rezumat<br />

Uzul antipsihoticului este recunoscută <strong>de</strong> psih<strong>of</strong>armacologia actuală în multiple<br />

entităţi nozologice psihiatrice.<br />

Lărgirea spectrului <strong>de</strong> utilizare <strong>de</strong> la tulburarea psihotică si la tulburarea <strong>de</strong><br />

conversie a antipsihoticului este în concordanţă cu suportul biochimic, un rol<br />

important jucându-l interacţiunile funcţionale la nivel joncţional a diferitelor linii <strong>de</strong><br />

neuromediator.<br />

Tulburarea <strong>de</strong> conversie în special cea cu factori asociaţi <strong>de</strong> prognostic nefavorabil,<br />

suscită la utilizarea <strong>de</strong> schemă terapeutică cu impact relativ rapid pe simptom şi<br />

căutarea unei modalităţi <strong>de</strong> îmbunătăţire a predicţiei negative <strong>de</strong> evoluţie.<br />

Experienţa noastră clinică a evi<strong>de</strong>nţiat rezultate în abordarea psih<strong>of</strong>armaceutică cu<br />

antipsihotic din generaţia a II-a în doze terapeutice minime, <strong>de</strong>sprinzând astfel<br />

oportunitatea utilizării acestuia ca alternativă la terapiile complementare.<br />

Cuvinte cheie: conversie, antipsihotic din generaţia a II-a, prognostic.<br />

SECOND GENERATION ANTIPSYCHOTICS IN<br />

THE TREATMENT OF CONVERSION DISORDERS<br />

Abstract<br />

The use <strong>of</strong> antipsychotic is wi<strong>de</strong>ly recognized in the present psychopharmacology for<br />

several psychiatric nosologic entities.<br />

Enlarging the usage spectrum <strong>of</strong> the antipsychotic from the psychotic disor<strong>de</strong>r to the<br />

conversion disor<strong>de</strong>r is in accordance with the biochemical support, an important<br />

role being played by the functional interactions at the level <strong>of</strong> junctions <strong>of</strong> different<br />

neuro-mediator lines.<br />

The conversion disor<strong>de</strong>r, especially the one with associated factors <strong>of</strong> unfavorable<br />

prognosis, leads to using a therapeutic scheme with a relatively rapid impact on the<br />

symptom and searching for a method to improve the negative evolution prediction.<br />

Our clinical experience highlighted results in the psycho-pharmaceutical approach<br />

with second generation antipsychotic in minimal therapeutic doses, thus proving the<br />

opportunity <strong>of</strong> using it as an alternative to complementary therapies.<br />

Key words: conversion, second generation antipsychotic, prognosis.<br />

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