26.04.2013 Views

jurnalul român de psihofarmacologie romanian journal of ...

jurnalul român de psihofarmacologie romanian journal of ...

jurnalul român de psihofarmacologie romanian journal of ...

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Jurnalul Român <strong>de</strong> Psih<strong>of</strong>armacologie<br />

Romanian Journal <strong>of</strong> Psychopharmacology<br />

Vol. 6, Nr. 1, 2<br />

Cu toate că doar cinci agenţi au fost aprobaţi <strong>de</strong> către FDA pentru tratamentul simptomatic<br />

al tulburărilor cognitive, mulţi alţi compusi farmacologici au fost evaluaţi si continua sa fie evaluaţi<br />

in multiple trialuri clinice ca potenţiale terapii modificatoare a evoluţiei bolii.<br />

Bibliografie:<br />

1. Winblad, B., 2001 – Maintaining functional and behavioral abilities in Alzheimer<br />

Disease. Alzheimer Disease and Ass Disor<strong>de</strong>rs, vol 15, suppl 1, 34-40.<br />

2. Santaguida P, Raina P, Booker L, Patterson C, Baldassarre F, Cowan D, Gauld M,<br />

Levine M, Unsal A, 2004 – Pharmacological Treatment <strong>of</strong> Dementia, AHRQ Publication<br />

No. 04-E018-2.<br />

3. Siemers E, Quinn J, Kaye J, et al., 2004 – Effect <strong>of</strong> LY450139, a functional gammasecretase<br />

inhibitor, on plasma and cerebrospinal fluid concentrations A-beta and<br />

cognitive functioning in patients with mild to mo<strong>de</strong>rate Alzheimer's disease. Neurol.,<br />

62(suppl5), A174. Abstract S17.001.<br />

4. Schenk D, Barbour R, Dunn W, et al., 1999 – Immunization with amyloid-beta attenuates<br />

Alzheimer-disease-like pathology in the PDAPP mouse. Nature, 400,173-177.<br />

5. Satou T, Itoh T, Tamai Y, Oh<strong>de</strong> H, An<strong>de</strong>rson AJ and Hashimoto S, 2000 – Neurotrophic<br />

effects <strong>of</strong> FPF-1070 (Cerebrolysin) on cultured neurons from chicken embryo dorsal<br />

root ganglia, ciliary ganglia, and sympathetic trunks. J Neural Transm., 107, 1253-62.<br />

6. Windisch M, 2000 – Approach towards an integrative drug treatment <strong>of</strong> Alzheimer's<br />

disease. J Neural Transm Suppl., 59, 301-13.<br />

7. Ruether E, Husmann R, Kinzler E, Diabl E, Klingler D, Spatt J, Ritter R, Schmidt R,<br />

Taneri Z, Winterer W, Koper D, Kasper S, Rainer M and Moessler H, 2001 – A 28week,<br />

double-blind, placebo-controlled study with Cerebrolysin in patients with mild to<br />

mo<strong>de</strong>rate Alzheimer's disease. Int Clin Psychopharmacol. 16, 253-63.<br />

8. Ruether E, Alvarez XA, Rainer M and Moessler H, 2002 – Sustained improvement <strong>of</strong><br />

cognition and global function in patients with mo<strong>de</strong>rately severe Alzheimer's disease: a<br />

double-blind, placebocontrolled study with the neurotrophic agent Cerebrolysin. J<br />

Neural Transm Suppl. 265-75.<br />

9. Masliah E, Armasolo F, Veinbergs I, Mallory M and Samuel W, 1999 – Cerebrolysin<br />

ameliorates performance <strong>de</strong>ficits, and neuronal damage in apolipoprotein E-<strong>de</strong>ficient<br />

mice. Pharmacol Biochem Behav., 62, 239-45.<br />

19

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!