Clujul Medical - Iuliu Haţieganu

Clujul Medical 2006 vol. LXXX - nr. 1
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The overlap of functional digestive disorders
ELENI STERGIOPOULOU, DUMITRU DUMITRAŞCU
Summary
We aimed to evaluate the prevalence and the types of associations of
functional digestive disorders by a standardized clinical analysis (50 items). On a
sample of 220 patients chosen from the files of four gastroengerological units in
Athens, Greece, we detected multiple symptom associations in 85% cases. The most
common were the following associations: heartburn-epigastric pain syndrome (“ulcer
like dyspepsia”), irritable bowel syndrome-posprandial distress syndrome, gallbladder
dysfunction-posptrandial distress syndrome. These interferences between different
functional gastrointestinal disorders may variate in time. After a one-year follow-up,
several symptomatic changes with the alternation of the main complaints have been
detected, sometimes with a change in the topographical presentation. These findings
suggest a nosographic unity of the functional gastrointestinal disorders, generated by
common factors and having the same pathogenic background. Therefore a complete
clinical evaluation of the functional patients is required in order to enable the best
individualized management.
Key words: functional gastrointestinal disorders, overlap, dyspepsia, irritable
bowel syndrome
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