Materiais moleculares funcionais contendo n-heterociclos - capes

LSYC146630 LSYC_036_007 Techset Composition Ltd, Salisbury, U.K. 1/20/2006[1,2,3]-Triazole Liquid Crystals 953Scheme 1.Regioselectivity in 1,3-dipolar cycloaddition for [1,2,3]-triazoles.In this work, the synthesis of the targets was carried out as described inScheme 2. The aryl azide 2 was prepared by nucleophylic displacementfrom diazonium salt of 4-N-decyloxyaniline. Terminal aryl acetylenes 1a–ewere synthesized from their respective aryl halides (bromide or iodide) viaa palladium-copper-catalyzed cross-coupling reaction (Sonogashira’scoupling) using the commercial 2-methyl-3-butyn-2-ol followed by protectivegroup elimination, with acetone. [15] To get the desired asymmetrical bent coreScheme 2. Synthesis of the targets 3a–e by Cu(I)-catalyzed 1,3-dipolar cycloaddition(click reaction).