PARTE EXPERIMENTALJ 11,3; 9,1 e 5,8 Hz, H-5), 4,47 (t, 1H, J 8,5 Hz, H-5), 4,56 (ddd, 1H, J 11,3;8,6 e 5,8 Hz, H-3), 6,07 (d, NH, J 4,9 Hz).RMN <strong>de</strong> 13 C (125,69 MHz, CDCl 3 , TMS): δ 14,1 (C-12’); 22,7 (C-11’); 24,2; 25,4; 28,8; 29,2; 31,9; 29,4; 29,4 (C-10’ to C-4’); 29,5 (C-3’);35,3 (C-2’); 66,1 (C-5); 30,7 (C-4); 49,2 (C-3); 173,8 (C-1’); 175,6 (C-2).12'11'10'9'8'7'6'5'4'3'2'O1'NH4 53 12HOO(S)-(-)-N-<strong>do</strong><strong>de</strong>canoil-homosserina lactona. Rendimento: 23,5 mg; 79,3%.[α] 20 D –7,0º (c. 0,16; MeOH).CG-EM (IE, 70 eV) m/z 283 (M +. , 4%), 156 (19 %), 143 (100%), 125(15%), 102 (18%), 83 (12%), 57 (35%), 43 (17%).IV (KBr): 3326, 2952, 2926, 1776, 1647, 1550, 1172, 1112 cm -1 .RMN <strong>de</strong> 1 H (300,06 MHz, CDCl 3 , TMS): δ 0,88 (t, 3H, J 6,2 Hz, H-12’), 1,26 (m, 16H, H-11’ a H-4’), 1,66 (m, 2H, H-3’), 2,13 (m, 1H, H-4),2,25 (t, 2H, J 7,4 Hz, H-2’), 2,87 (m, 1H, H-4), 4,29 (ddd, 1H, J 11,4; 9,5 e5,9 Hz, H-5), 4,47 (t, 1H, J 8,4 Hz, H-5), 4,54 (ddd, 1H, J 11,4; 8,4 e 5,5 Hz,H-3), 6,05 (s, NH, largo).RMN <strong>de</strong> 13 C (75,45 MHz, CDCl 3 , TMS): δ 14,1 (C-12’); 22,7 (C-11’); 25,5; 29,3; 29,4; 29,4; 31,9; 29,5; 29,6 (C-10’ to C-4’); 29,6 (C-3’);36,2 (C-2’); 66,1 (C-5); 30,8 (C-4); 49,3 (C-3); 173,7 (C-1’); 175,4 (C-2).157
PARTE EXPERIMENTAL13'12'11'10'9'8'7'6'5'4'3'2'O1'NH4 5312OO(±)-N-tri<strong>de</strong>canoil-homosserina lactona. Rendimento: 24,6 mg; 78,9%. R f 0,625 (CH 2 Cl 2 /AcEt 1/1). CG-EM (IE, 70 eV) m/z 297 (M +. , 3%), 156(19 %), 143 (100%), 125 (13%), 102 (18%), 83 (12%), 57 (31%), 43 (15%).IV (KBr): 3320, 2920, 2850, 1776, 1645, 1550, 1168, 1012 cm -1 .RMN <strong>de</strong> 1 H (300,06 MHz, CDCl 3 , TMS): δ 0,88 (t, 3H, J 6,6 Hz, H-12’), 1,26 (m, 18H, H-11’ a H-4’), 1,64 (m, 2H, H-3’), 2,14 (m, 1H, H-4),2,25 (t, 2H, J 7,0 Hz, H-2’), 2,83 (m, 1H, H-4), 4,28 (ddd, 1H, J 11,0; 9,2 e5,9 Hz, H-5), 4,46 (t, 1H, J 8,8 Hz, H-5), 4,57 (ddd, 1H, J 11,0; 8,8 e 6,2 Hz,H-3), 6,22 (d, NH, J 5,1 Hz).RMN <strong>de</strong> 13 C (75,45 MHz, CDCl 3 , TMS): δ 14,1 (C-13’); 22,7 (C-12’); 24,8; 25,5; 29,2; 29,3; 29,5; 29,6; 30,5 (C-4’ a C-11’, com sinaissobrepostos); 31,9 (C-3’); 36,2 (C-2’); 66,1 (C-5); 30,5 (C-4); 49,2 (C-3);173,7 (C-1’); 175,5 (C-2).14'13'12'11'10'9'8'7'6'5'4'3'2'O1'NH4 53 12OO(±)-N-tetra<strong>de</strong>canoil-homosserina lactona. Rendimento: 30,6 mg; 93,7%. R f 0,625 (CH 2 Cl 2 /AcEt 1/1). CG-EM (IE, 70 eV) m/z 311 (M +. , 3%), 156(20 %), 143 (100%), 125 (13%), 102 (19%), 101 (11%), 83 (12%), 57(32%), 43 (17%).IV (KBr): 3326, 2917, 2853, 1770, 1634, 1533, 1169, 1006 cm -1 .158
- Page 3 and 4:
VDEDICATÓRIADEDICO ESTE TRABALHO
- Page 5 and 6:
VIIIBraga, Dr. José Augusto R. Rod
- Page 7 and 8:
XPOMINI, A. M. ; CABEÇA, L. F. ; C
- Page 9 and 10:
XIIde cadeia longa. Realizou-se tam
- Page 11 and 12:
XIVacyl-HSLs. We have also studied
- Page 13 and 14:
XVINBNOEODPpmR fRMNROERLUSTDSAMTMST
- Page 15 and 16:
XVIII3.3.4.2. Síntese da (S)-N-(2E
- Page 17 and 18:
XX5.4.10. Co-injeções das acil-HS
- Page 19 and 20:
___________________________________
- Page 21 and 22:
___________________________________
- Page 23 and 24:
___________________________________
- Page 25 and 26:
___________________________________
- Page 27 and 28:
___________________________________
- Page 29 and 30:
___________________________________
- Page 31 and 32:
___________________________________
- Page 33 and 34:
___________________________________
- Page 35 and 36:
___________________________________
- Page 37 and 38:
___________________________________
- Page 39 and 40:
___________________________________
- Page 41 and 42:
___________________________________
- Page 43 and 44:
___________________________________
- Page 45 and 46:
___________________________________
- Page 47 and 48:
___________________________________
- Page 49 and 50:
___________________________________
- Page 51 and 52:
___________________________________
- Page 53 and 54:
___________________________________
- Page 55 and 56:
___________________________________
- Page 57 and 58:
___________________________________
- Page 59 and 60:
___________________________________
- Page 61 and 62:
___________________________________
- Page 63 and 64:
___________________________________
- Page 65 and 66:
___________________________________
- Page 67 and 68:
___________________________________
- Page 69 and 70:
___________________________________
- Page 71 and 72:
___________________________________
- Page 73 and 74:
___________________________________
- Page 75 and 76:
___________________________________
- Page 77 and 78:
___________________________________
- Page 79 and 80:
___________________________________
- Page 81 and 82:
___________________________________
- Page 83 and 84:
___________________________________
- Page 85 and 86:
___________________________________
- Page 87 and 88:
___________________________________
- Page 89 and 90:
___________________________________
- Page 91 and 92:
___________________________________
- Page 93 and 94:
___________________________________
- Page 95 and 96:
___________________________________
- Page 97 and 98:
___________________________________
- Page 99 and 100:
___________________________________
- Page 101 and 102:
___________________________________
- Page 103 and 104:
___________________________________
- Page 105 and 106:
___________________________________
- Page 107 and 108:
___________________________________
- Page 109 and 110:
___________________________________
- Page 111 and 112:
___________________________________
- Page 113 and 114:
___________________________________
- Page 115 and 116: ___________________________________
- Page 117 and 118: ___________________________________
- Page 119 and 120: ___________________________________
- Page 121 and 122: ___________________________________
- Page 123 and 124: ___________________________________
- Page 125 and 126: ___________________________________
- Page 127 and 128: ___________________________________
- Page 129 and 130: ___________________________________
- Page 131 and 132: ___________________________________
- Page 133 and 134: ___________________________________
- Page 135 and 136: ___________________________________
- Page 137 and 138: PARTE EXPERIMENTAL5. PARTE EXPERIME
- Page 139 and 140: PARTE EXPERIMENTAL• Espectroscopi
- Page 141 and 142: PARTE EXPERIMENTAL5.1.2. Meios de c
- Page 143 and 144: PARTE EXPERIMENTAL5.1.4. Cepas bact
- Page 145 and 146: PARTE EXPERIMENTAL(S)-N-heptanoil-h
- Page 147 and 148: PARTE EXPERIMENTAL(R)-(+)-N-heptano
- Page 149 and 150: PARTE EXPERIMENTAL5.3. Avaliação
- Page 151 and 152: PARTE EXPERIMENTALhexano, diclorome
- Page 153 and 154: PARTE EXPERIMENTAL4,47 (t, 1H, J 9,
- Page 155 and 156: PARTE EXPERIMENTAL13' 11' 9' 7' 5'O
- Page 157 and 158: PARTE EXPERIMENTALHinton contendo o
- Page 159 and 160: PARTE EXPERIMENTALno caso dos meios
- Page 161 and 162: PARTE EXPERIMENTAL(S)-N-tetradecano
- Page 163 and 164: PARTE EXPERIMENTALAs acil-HSLs fora
- Page 165: PARTE EXPERIMENTAL5% (2 x 6 mL), bi
- Page 169 and 170: PARTE EXPERIMENTALsinais sobreposto
- Page 171 and 172: PARTE EXPERIMENTALóleo e ferveu-se
- Page 173 and 174: PARTE EXPERIMENTALRMN de 13 C (75,4
- Page 175 and 176: PARTE EXPERIMENTAL(S)-(2E)-N-dodece
- Page 177 and 178: PARTE EXPERIMENTAL(S)-3-oxo-(7Z)-N-
- Page 179 and 180: PARTE EXPERIMENTAL5.4.9.3. Obtenç
- Page 181 and 182: PARTE EXPERIMENTALIV (KBr): 3318, 3
- Page 183 and 184: PARTE EXPERIMENTALisotermicamente a
- Page 185 and 186: PARTE EXPERIMENTALprocedimento, por
- Page 187 and 188: REFERÊNCIAS BIBLIOGRÁFICAS6. REFE
- Page 189 and 190: REFERÊNCIAS BIBLIOGRÁFICASClusia
- Page 191 and 192: REFERÊNCIAS BIBLIOGRÁFICASENGEBRE
- Page 193 and 194: REFERÊNCIAS BIBLIOGRÁFICASLAMBAIS
- Page 195 and 196: REFERÊNCIAS BIBLIOGRÁFICASusing l
- Page 197 and 198: REFERÊNCIAS BIBLIOGRÁFICASXylella
- Page 199 and 200: ___________________________________
- Page 201 and 202: ___________________________________
- Page 203 and 204: ___________________________________
- Page 205 and 206: ___________________________________
- Page 207 and 208: ___________________________________
- Page 209 and 210: ___________________________________
- Page 211 and 212: ___________________________________
- Page 213 and 214: ___________________________________
- Page 215 and 216: ___________________________________
- Page 217 and 218:
___________________________________
- Page 219 and 220:
___________________________________
- Page 221 and 222:
___________________________________
- Page 223 and 224:
___________________________________
- Page 225 and 226:
___________________________________
- Page 227 and 228:
___________________________________
- Page 229 and 230:
___________________________________
- Page 231 and 232:
___________________________________
- Page 233 and 234:
___________________________________
- Page 235 and 236:
___________________________________
- Page 237 and 238:
___________________________________
- Page 239 and 240:
___________________________________
- Page 241 and 242:
___________________________________
- Page 243 and 244:
___________________________________
- Page 245 and 246:
___________________________________
- Page 247 and 248:
___________________________________
- Page 249 and 250:
___________________________________
- Page 251 and 252:
___________________________________
- Page 253 and 254:
___________________________________
- Page 255 and 256:
___________________________________
- Page 257 and 258:
___________________________________
- Page 259 and 260:
___________________________________
- Page 261 and 262:
___________________________________
- Page 263 and 264:
___________________________________
- Page 265 and 266:
___________________________________
- Page 267 and 268:
___________________________________
- Page 269 and 270:
___________________________________
- Page 271 and 272:
___________________________________
- Page 273 and 274:
___________________________________