armando mateus pomini - Biblioteca do Instituto de QuÃmica - Unicamp
armando mateus pomini - Biblioteca do Instituto de QuÃmica - Unicamp
armando mateus pomini - Biblioteca do Instituto de QuÃmica - Unicamp
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
PARTE EXPERIMENTAL7' 5'O O3'8' 6' 4' 2'1'NH4 53 1 2HO(S)-N-(3-oxo-octanoil)-homosserina lactona. Rendimento global: 38,7 %. Osda<strong>do</strong>s <strong>de</strong> CG-EM, RMN <strong>de</strong> 1 H e 13 C são idênticos aos obti<strong>do</strong>s para a (±)-N-(3-oxo-octanoil)-HSL. [α] 20 D –17º (c. 0,53 MeOH).O7' 5'O O3'8' 6' 4' 2'1'NH4 5312HO(R)-N-(3-oxo-octanoil)-homosserina lactona. Rendimento global: 67,3 %.Os da<strong>do</strong>s <strong>de</strong> CG-EM, RMN <strong>de</strong> 1 H e 13 C são idênticos aos obti<strong>do</strong>s para a (±)-N-(3-oxo-octanoil)-HSL. [α] 20 D +16º (c. 0,51 MeOH).O12'11'10'9'8'7'6'5'4'O3'2'O1'NH4 53 12OO(±)-N-(3-oxo-<strong>do</strong><strong>de</strong>canoil)-homosserina lactona. Rendimento global:39,5 %. R f 0,473 (AcEt 100%). CG-EM (IE, 70 eV) <strong>de</strong>composição.IV (KBr). 3298, 2925, 2850, 1782, 1721, 1641, 1546, 1382, 1178,1019, 721 cm -1 .RMN <strong>de</strong> 1 H (300,06 MHz, CDCl 3 , TMS): δ 0,87 (t, 3H, J 6,2 Hz, H-12’); 1,26 (m, 12H, H-11’, H-10’, H-9’, H-8’, H-7’, H-6’); 1,58 (quinteto,2H, J 7,0 Hz, H-5’); 2,25 (m, 1H, H-4); 2,53 (t, 2H, J 7,3 Hz, H-4’); 2,75(m, 1H, H-4); 3,47 (s, 2H, H-2’); 4,28 (ddd, 1H, J 11,4; 9,5 e 6,2 Hz, H-5);143
Change language