Visualizar Tese - Instituto de Biociências - Unesp

Anexo 4. Genes e miRNAs mapeados nas regiões significativas de ganhos e perdas genômicos nas amostras de Leiomiomas Uterinos.Região Start End Evento Símbolo do gene miRNAs1p36.33-p36.32 1,921,978 3,562,051 Perda >10 (TP73, ARHGEF16) hsa-mir-551a1p31.1 82,163,689 84,655,179 Perda DNASE2B, LPHN2, PRKACB, SAMD13, TTLL7, UOX1q21.3 149,836,310 150,010,690 Ganho SNX27, TNRC4, RIIAD1, CELF3, MRPL9, OAZ31q41 212,893,807 214,014,200 Perda CENPF, KCNK2, KCTD3, MIR548F3, USH2A2q35 217,253,192 219,351,693 Ganho >10 (IGFBP5, CXCR1, CXCR2) hsa-mir-26b4p14 40,185,743 40,457,450 Perda RBM47, NSUN74q13.1-q13.2 60,129,993 68,031,967 Perda CENPC1, EPHA5, LPHN3, TECRL hsa-mir-12694q21.21 80,461,995 82,110,583 Perda GDEP, PRDM8, ANTXR2, FGF5, ARD1B, NAA11, GK24q28.3 132,220,774 135,650,424 Perda PABPC4L, PCDH105q31.1-q31.2 134,274,907 135,585,827 Perda >10 (TGFBI, CXCL14) hsa-mir-8866p21.32 31,962,130 32,132,073 Ganho >10 hsa-mir-12366q13 73,782,170 74,568,779 Ganho >106q16.3 102,041,584 103,869,362 Ganho GRIK27p12.2 50,138,493 50,702,500 Perda ZNFN1A1, FIGNL1, IKZF1, DDC, GRB107q22.1 98,769,492 102,068,500 Ganho >10 hsa-mir-25, hsa-mir-93,hsa-mir-106b, hsa-mir-548o7q22.1-q22.2 104,284,386 105,139,642 Perda ATXN7L1, EFCAB10, LHFPL3, LOC100216545, LOC723809, MLL5,PUS7, RINT1, SRPK27q31.33 124,268,700 125,951,548 Perda GRM8, POT18p12-p11.23 37,606,006 38,685,823 Ganho >10 (STAR, FGFR1)