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Visualizar Tese - Instituto de Biociências - Unesp

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Dimitrova IK et al. Fertil Steril,91, 2650-2663, 2009LU (3) x MM (3)uma paciente pósmenopáusicaFBLN1, DSG2, PRKCB, MMP11 e MMP14,FBLN2, FBLN3, EFEMP1,FBLN5, MST4, MMP7RT-PCRWestern blotIHQHodge JC et al.Am J Pathol, 172, 1403-1410,2008LU plexiformes (6)Análise cariotípicapréviaFISH para o HMGA2UBC, RDBP, CYC1, COX5B, CKS1B, DSS1,TMSB10PIPPIN, ENPP1, GRIA2, CRMP1, TGFB3, NBL1, LAMA3, MORF4L2, KANK, CTNND1,SETDB1, TACR2, GSTM4, APOD, TIMP3, DPP6, DVL3, VCL, TPM4, GTF2I, THRSP, ID2,STAT4 e MMP2qRT-PCRIHQCrabtree JS et al.Cancer Res, 69, 6171-6178,2009LU (15) X MM (16) <strong>de</strong>ratosLU (23) X MM (23)humanosGenes da via mTOR; GRIN2B, CAPN6, MMP11, e MMP13Western blot,IHQBorsari R et al.Fertil Steril, 94, 1072-1077,201030 pacientes nulíparascom LUDois grupos - tratadasx não tratadasCYR61, SULF 2, HMGN1, and EGR1 e WIF 1qRT-PCRJiang Y et al.Syst Biol Reprod Med, 56, 318–326, 2010LU (42) x MM (42)CCN1,CCN2,AXL,PTK6,NRP1,VEGFA,JAK3,AVEN,BAG1,FGF9,CCNE2,LYN,EPHA7,FLT1,MET,FES,FGF23,IGFBP5,IGF2,EPHA8,PDGFC,EPHB4,EFNA4,BOK,EFNB2,HBEGF,BCL2L1,PGF,BCL2L14,CCND3,MDK,BCL2L12,APAF1,BCL2L11,PRAD1,FGFR1,EFNB3,PTK7,qRT-PCR*Alguns estudos não informaram a fase do ciclo das pacientes. LU = leiomiomas uterinos; LMS = leiomiosarcomas; MM = miométrio adjacente; IHQ =imunohistoquímica; RT-PCR = PCR qualitativa; qRT-PCR = PCR quantitativa em tempo real;Ver<strong>de</strong> = expressão diminuída; Vermelho = expressãoaumentada.

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