Karen Tereza Altieri - Faculdade de Odontologia - Unesp
Karen Tereza Altieri - Faculdade de Odontologia - Unesp
Karen Tereza Altieri - Faculdade de Odontologia - Unesp
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<strong>Altieri</strong> KT. Effectiveness of two disinfectant solutions and microwave irradiation in<br />
disinfecting complete <strong>de</strong>ntures contaminated with methicillin-resistant<br />
Staphylococcus aureus (MRSA) [Dissertação <strong>de</strong> Mestrado]. Araraquara:<br />
<strong>Faculda<strong>de</strong></strong> <strong>de</strong> <strong>Odontologia</strong> da UNESP; 2011.<br />
Abstract<br />
Infections caused by antibiotic-resistant bacteria have been<br />
recognized as a predominant risk factor for mortality in el<strong>de</strong>rly patients and<br />
approximately 50 % of these infections have been related to methicillin-resistant<br />
Staphylococcus aureus (MRSA). This microorganism, when present in the<br />
<strong>de</strong>nture biofilm, can be released into the oral fluids and aspirated into the lower<br />
respiratory tract, thus causing infections such as aspiration pneumonia. The<br />
present study compared the efficacy of 1 % sodium hypochlorite, 2 %<br />
chlorhexidine gluconate, and microwave irradiation in disinfecting simulated<br />
complete <strong>de</strong>ntures and circular specimens of acrylic resin <strong>de</strong>nture base material<br />
(10 x 2 mm) contaminated with MRSA. Thirty-six <strong>de</strong>ntures and 36 specimens<br />
were ma<strong>de</strong>, sterilized, inoculated with MRSA (10 7<br />
cfu/mL), and incubated at<br />
37 °C (for 24 and 48 h, respectively). After incubation, <strong>de</strong>ntures and specimens<br />
were divi<strong>de</strong>d into 4 groups of study (n=9): PC - positive control, consisting of<br />
<strong>de</strong>ntures and specimens not disinfected; HY - soaking in 1 % sodium<br />
hypochlorite solution for 10 min; CHL - soaking in 2 % chlorhexidine gluconate<br />
solution for 10 min; and MW - irradiating by microwave for 3 min at 650W. The<br />
effectiveness of the disinfection procedures was assessed cell viability