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Síntese de ácido graxo

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<strong>Síntese</strong> <strong>de</strong> <strong>ácido</strong> <strong>graxo</strong> ocorre no<br />

citosol<br />

• Deve ter uma fonte <strong>de</strong> acetil-CoA<br />

• Deve ter acetil-CoA na mitocôndria<br />

• Citrato-malato-piruvato provem unida<strong>de</strong>s <strong>de</strong><br />

acetato citosólico e equivalentes redutores para<br />

síntese <strong>de</strong> <strong>ácido</strong> <strong>graxo</strong>.<br />

Citrate synthase<br />

Pyruvate<br />

carboxylase<br />

Citrate Lyase<br />

Malate<br />

<strong>de</strong>hydrogenase<br />

Malate Enzyme

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