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com a A em uma proporção tal que A constitua 20% da população total, qual será a freqüência da<br />

anomalia em discussão na população híbrida?<br />

R 28. 0,08: 10.000 porque:<br />

q²A = 0,0001; qA = 0,01<br />

q²B = 0,000001; qB = 0,001<br />

q = (0,20 × 0,01) + (0,80 × 0,001) = 0,0028<br />

q 2 = 0,000008<br />

REFERÊNCIAS<br />

Aird, J., Bentall, H.H. & Roberts, J.A.F. A relationship between cancer of stomach and ABO blood groups. Brit.<br />

Med. J. 1: 794-801, 1953.<br />

Allison, A.C. Protection affor<strong>de</strong>d by sickle-cell trait against subtertian malarial infection. Brit. Med. J 1: 290-294,<br />

1954a.<br />

Allison, A.C. The distribution of the sickle-cell trait in East Africa and elsewhere and its apparent relationship to the<br />

inci<strong>de</strong>nce of subtertian malaria. Tr. Roy. Soc. Trop. Med. Hyg. 48: 312-318, 1954b.<br />

Beiguelman, B. Taste sensitivity to PTC among Japanese immigrants in Brazil. Rev. Bras. Biol. 22: 93-97, 1962a.<br />

Beiguelman, B Reação à fenil-tio-carbamida (PTC) e lepra. Rev. Bras. Lepr 30: 111-124, 1962 b.<br />

Beiguelman, B. Grupos sangüíneos e lepra. Rev. Bras. Lepr. 31: 34-44, 1963.<br />

Beiguelman, B. Sistema ABO e epi<strong>de</strong>miologia <strong>de</strong> lepra. Rev. Paul. Med. 65: 80-86, 1964a.<br />

Beiguelman, B. Taste sensitivity to pheny1thiourea among patients affected with both tuberculosis and leprosy. Acta<br />

Genet. Med. Gemellol. 13: 190-192, 1964b.<br />

Beiguelman, B. Taste sensitivity to pheny1thiourea and leprosy. Acta Genet. Med. Gemellol. 13: 193-196, 1964c.<br />

Beiguelman, B. Um método simples para o estudo da mistura racial no Brasil. Ciência e Cultura 32(Supl.): 745,<br />

1980.<br />

Beiguelman, B. & Marchi, A. The frequency of blood groups among Japanese immigrants in Brazil. Am. J. Phys.<br />

Anthrop. 20:29-31, 1962.<br />

Beutler, E. The hemolytic effect of primaquine and related compounds. A review. Blood 14: 103-139,1959.<br />

Beutler, E., Dern, RJ. & Flanagan, C.L. Effect of sickle-cell trait on resistance to malaria. Brit. Med. J. 1: 1189-<br />

1191, 1955.<br />

Biocca, E. & Ottensooser, F. Estudos etnobiológicos sobre os índios da região do Alto Rio Negro: Amazonas. I.<br />

Grupos sangüíneos comuns e fatores MN. Arq. Biol. (São Paulo) 28: 111-118, 1944.<br />

Brues, A.M. Selection and polymorphsm in the A-B-0 blood groups. Am. J. Phys. Anthrop. 12: 559-557, 1954.<br />

Cunha, A.X. & Morais, M.X Os grupos sangüíneos dos portugueses. Contribuição ao Estudo da Antropologia<br />

Portuguesa, 7:17-36,1959, cf. Saldanha, P.H. op. cit.<br />

Dahlberg, G. Inbreeding in man. Genetics 14: 421-454, 1929.<br />

Darwin, C. Origem das espécies. Ed. Itatiaia Ltda./EDUSP, S. Paulo, 1985.Tradução <strong>de</strong> AMADO, E., da 1 a edição<br />

<strong>de</strong> On the origin of species by means of natural selection, John Murray, Abennale Street, London, 1859.<br />

194<br />

185<br />

185

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