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Hemofilia A - Genética - ufcspa

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43. Lakich D, Kazazian HH Jr, Antonarakis SE, Gitshier J. Inversions disrupting the fac-<br />

tor VIII gene are common cause of severe hemophilia A. Nat Genet 1993;5:236-41.<br />

44. Gitschier J, Lawn RM, Rotblat F, Goldman E, Tuddenham EGD. Antenatal diagnosis<br />

and carrier detection of haemophilia A using factor VIII gene probe. Lancet 1985;1:1093-<br />

4.<br />

45. Mannucci PM. The choice of plasma-derived clotting factor concentrates. Baillieres<br />

Clin Haematol 1996;9:273-90.<br />

46. Mannucci PM, Gdovin S, Gringeri A, et al. Transmission of hepatitis A to patients<br />

with hemophilia by factor VIII concentrates treated with organic solvent and detergent to<br />

inactive viruses. Ann Intern Med 1994;120:1-7.<br />

47. Schartz RS, Abildgaard CF, Aledort LM, et al. Human recombinant DNA-derived an-<br />

tihemophilic factor (factor VIII) in the treatment of hemophilia A. N Engl J Med<br />

1990:323:1800-5.<br />

48. Lusher JM, Arkin S, Abildgaard CF, Kogenate Previously Untreated Patient Study<br />

Group. Recombinant factor VIII for the treatment of previously untreated patients with<br />

hemophilia A: safety, efficacy, and development of inhibitors. N Engl J Med<br />

1993:328:453-9.<br />

49. Bray GL, Gomperts ED, Courter S, et al. A multicenter study of recombinant factor<br />

VIII (Recombinate): safety, efficacy, and inhibitor risk in previously untreated patients<br />

with hemophilia A. Blood 1994;84:2428-35.<br />

50. White GC II, Courter S, Bray GL, Lee M, Gomperts ED. A multicenter study of re-<br />

combinant factor VIII (Recombinate) in previously treated patients with hemophilia A.<br />

Thromb Hamost 1997;77:660-7.<br />

51. Luscher JM. Factor VIII inhibitors: etiology, characerization, natural history, and<br />

management. Ann N Y Acad Sci 1987;509:89-102.<br />

52. McMillan CW, Shapiro SS, Whiteshurst D, Hoyer LW, Rao AV, Lazerson J. The<br />

natural history of factor VIII:C inhibitors in patients with hemophilia A: a national coop-<br />

erative study. II. Observations on the initial development of factor VIII:C inhibitors. Blood<br />

1988;71:344-8.<br />

53. Lewis JH, Bontempo FA, Spero JA, Ragni, MV, Starzl, TE. Liver transplantation in a<br />

hemophiliac. New Eng. J. Med 1985;312: 1189-1190.<br />

48

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