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Faculdade de Medicina Veterinária - Hospital Veterinário Montenegro

Faculdade de Medicina Veterinária - Hospital Veterinário Montenegro

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Cláudia Freitas Estadiamento da Doença Renal Crónica em Felinos 2010<br />

Staging of Feline Chronic Kidney Disease<br />

Abstract<br />

Chronic Kidney Disease (CKD) is a disease with insidious evolution, progressive and<br />

irreversible, common in our company animals. This is the most frequently diagnosed kidney<br />

disease in felines, responsible for high rates of morbidity and mortality, especially in ol<strong>de</strong>r<br />

cats. The International Renal Interest Society proposed a classification system for renal<br />

disease, in or<strong>de</strong>r to facilitate the implementation of appropriate clinical gui<strong>de</strong>lines for<br />

diagnosis, prognosis and therapy of this disease.<br />

This dissertation was <strong>de</strong>veloped from September 2009 to March 2010, as part of the<br />

curricular training in the Integrated Master <strong>de</strong>gree in Veterinary Medicine at the Veterinary<br />

<strong>Hospital</strong> <strong>Montenegro</strong>. This consisted of the characterization of a population sample of 25<br />

cats with CKD presented for consultation or hospitalized from January 2009 to March 2010,<br />

with special attention to the staging of all these patients and sub-staging of 6 felines. These<br />

animals were aged between 3 and 17 years, 48% of which <strong>de</strong>veloped anemia and 80% the<br />

cause of CKD has not been <strong>de</strong>termined. The average survival time of cats that died of this<br />

disease was 243 days. As for staging, none of the cats was in stage I, 44% were in stage II,<br />

40% in stage III and only 16% were in stage IV. According to the presence and severity of<br />

proteinuria, 50% of the cats were classified as proteinuric, 33,3% were non-proteinuric and<br />

16,7% were bor<strong>de</strong>rline proteinuric. In the sub-staging based in blood pressure, 50% had low<br />

risk, 33,3% minimum risk and only 16,7% had mo<strong>de</strong>rate risk. None of the cats had evi<strong>de</strong>nce<br />

of injuries/complications in target organs.<br />

This staging system continues to evolve through new research and clinical studies aimed at<br />

early diagnosis of kidney disease, which will allow the institution of preventive measures,<br />

treatment and monitoring that can slow disease progression, improving the quality of life of<br />

these patients.<br />

Key words: Chronic Kidney Disease, IRIS, staging, feline<br />

iii

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