carcinoma papilífero familiar de tireóide - Faculdade de Medicina ...

papillary carcinoma (FPC) 75% were females and 25% males. Average serum
TSH was 1.2±0.2 mU/L, free T4 1.3±0.3 ng/dL and TPOAb were positive in 25%.
Of the 18 patients who were not submitted to US, 8 had undergone
thyroidectomies previously. The remaining exams were abnormal in 68 cases
(54.4%): 49 (39.2%) had nodular disease of which 24 were solitary (19.2%) and 25
multinodular (20%).11 cases were classified as FPC: 7 had been operated
previously and the other 4 had multinodular glands. We found a prevalence of FPC
of 7.7% in the examined relatives and 19.2% in the examined families with an
obvious selection bias.No relationship between thyroid dysfunction or autoimmunity
and FPC could be established. There was a higher prevalence of multinodular
goiters.
Rio de Janeiro
Março/2008
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