Ciclo Celular: Introdução

Cdc2 = CDK1 !!
Alguns dos genes essenciais para divisão das leveduras codificavam
exatamente proteínas que mediavam a atividade
bioqímica/biológica do MPF
MPF was first known for its function, then as a protein and finally as a
gene. In contrast, CDC28 (S. cerevisiae) or cdc2 (S. pombe) was first
described as a gene with a known function and only later was the
protein identified. Cyclin was first discovered as a protein, then as a
gene and finally its function was known as a component of MPF”