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bei der Herzinsuffizienz

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„Gap junctions“<br />

Elektrisches Remodeling<br />

<strong>bei</strong> <strong>der</strong> <strong>Herzinsuffizienz</strong><br />

?<br />

I Na<br />

Na +<br />

Partielle<br />

„Gap junctions“<br />

Entkopplung<br />

+<br />

Fibrose<br />

P<br />

Connexine<br />

Cx43<br />

P<br />

Cx43<br />

SR<br />

Ca 2+<br />

Erregungsleitung<br />

P<br />

Cx43<br />

P<br />

Reentry<br />

Peters et al., Circulation 1993; 88:864; Kawara et al., Circulation 2001;104:3069; Akar et al., Circ Res 2004;95:117.

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