bei der Herzinsuffizienz
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Ryanodin-Kanal Remodeling<br />
<strong>bei</strong> <strong>der</strong> <strong>Herzinsuffizienz</strong><br />
Normal<br />
RyR2<br />
SR<br />
FKBP12.6<br />
DIASTOLE<br />
Ca 2+ -Leak<br />
Ca 2+<br />
Ser 2808 P<br />
P<br />
Ser 2814<br />
HF<br />
RyR2<br />
FKBP12.6<br />
SR<br />
Marx et al., Cell 2000;101:365; Wehrens et al., Circ Res 2004;94:e61; Ai et al., Circ Res 2005;97:1314.
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