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bei der Herzinsuffizienz

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Fokale (ektope) Aktivität <strong>bei</strong> <strong>der</strong> <strong>Herzinsuffizienz</strong><br />

I Ca,L<br />

Ca 2+<br />

Diastole<br />

NCX<br />

RyR2<br />

Ca 2+<br />

Ca 2+ Ca 2+<br />

Ca 2+<br />

Ca 2+ -Überladung?<br />

Ca 2+<br />

Ca 2+<br />

Ca 2+ Ca 2+<br />

Na +<br />

RyR2-Dysfunktion?<br />

Depolarisation<br />

„DADs“<br />

Getriggerte Aktivität<br />

Automatie<br />

Ektope Aktivität<br />

Sarkoplasmatisches Reticulum<br />

„DADs“ = Delayed Afterdepolarisations<br />

Späte Nachdepolarisationen

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