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Slow-wave: Konstant bølge af en mindre depolarisering uden AP. Dette betyder at der er en rytmisk<br />

strøm hele tiden i mave-tarmkanalen. Når Føde og væsker skal skubbes igennem vha.<br />

muskelarbejde begynder et AP at skyde der hvor slow wave peaker.<br />

HORMONE SOURCE TARGET ACTION<br />

Cholecystokinin I cells in duodenum and jejunum and<br />

neurons in ileum and colon<br />

Gastric-inhibitory<br />

peptide<br />

Pancreas<br />

Gallbladder<br />

↑ Enzyme secretion<br />

↑ Contraction<br />

K cells in duodenum and Jejunum Pancreas Exocrine: ↓ fluid absorption<br />

Endocrine: ↑ insulin release<br />

Gastrin G cells, antrum of stomach Parietal cells in body of<br />

Stomach<br />

Gastrin-releasing<br />

peptide<br />

Vagal nerve endings G cells in antrum of<br />

Stomach<br />

Glucagon α Cells of pancreatic islets of<br />

Langerhans<br />

↑ H + secretion<br />

↑ Gastrin release<br />

Liver ↑ Glycogenolysis<br />

↑ Gluconeogenesis<br />

Guanylin Ileum and colon Small and large intestine ↑ Fluid absorption<br />

Motilin Endocrine cells in upper GI tract Esophageal sphincter<br />

Stomach Duodenum<br />

Neurotensin Endocrine cells, wide-spread in GI<br />

tract<br />

Peptide YY Endocrine cells in ileum and colon Stomach<br />

Pancreas<br />

↑ Smooth-muscle contraction<br />

Intestinal smooth Muscle Vasoactive stimulation of<br />

histamine release<br />

↓ Vagally mediated acid<br />

secretion<br />

↓ Enzyme and fluid secretion<br />

Secretin S cells in small intestine Pancreas ↑ HCO3- and fluid secretion<br />

by pancreaticducts<br />

Somatostatin D cells of stomach and duodenum, δ<br />

cells of pancreatic islets<br />

Stomach ↓ Gastric-acid secretion<br />

Stomach ↓ Gastrin release<br />

Intestine ↓ Fluid absorption/↓ secretion<br />

↓ Smooth-muscle contraction<br />

Pancreas ↓ Endocrine/exocrine<br />

secretions<br />

Liver ↓ Bile flow<br />

Substance P Enteric neurons Enteric neurons Neurotransmitter<br />

Vasoactive intestinal<br />

peptide<br />

ENS neurons Small intestine ↓ Smooth-muscle relaxation<br />

↓ Secretion by small intestine<br />

Pancreas ↓ Secretion by pancreas

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