Jaarboek no. 89. 2010/2011 - Koninklijke Maatschappij voor ...

Natuurkundige voordrachten I Nieuwe reeks 89
Genetica en genoomonderzoek naar veroudering
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Referenties
1. Algemene informatie over DNA: www.natuurinforma-
tie.nl.
2. Oeppen J., Vaupel J.W. Demography. Broken limits to life
expectancy. Science 2002 May 10; 296(5570): 1029-31.
3. Hjelmborg J., et al. Genetic influence on human lifespan
and longevity. Hum Genet 2006 Apr; 119(3): 312-21.
4. Perls T., et al., Exceptional familial clustering for
extreme longevity in humans. J. Am Geriatr Soc 2000
Nov; 48(11): 1483-5.
5. Schoenmaker M, et al., Evidence of genetic enrichment
for exceptional survival using a family approach: the
Leiden Longevity Study. Eur J. Hum Genet 2006 Jan;
14(1): 79-84.
6. Westendorp R.G., et al., Nonagenarian siblings and
their offspring display lower risk of mortality and
morbidity than sporadic nonagenarians: The Leiden
Longevity Study. J. Am Geriatr Soc 2009 Sep; 57(9):
1634-7.
7. Rozing MP, et al., Human insulin/IGF-1 and familial
longevity at middle age. Aging (Albany NY) 2009 Aug;
1(8): 714-22.
8. Rozing M.P., et al., Favorable glucose tolerance and
lower prevalence of metabolic syndrome in offspring
without diabetes mellitus of nonagenarian siblings:
the Leiden longevity study. J Am Geriatr Soc 2010 Mar;
58(3): 564-9.
9. Heijmans B.T., et al., Lipoprotein particle profiles mark
familial and sporadic human longevity. PLoS Med 2006
Dec; 3(12): e495.
10. Beekman M., et al., Genome-wide association study
(GWAS)-identified disease risk alleles do not compromise
human longevity. Proc Natl Acad Sci USA 2010;107:
18046-18049.
11. Deelen J., et al., Genome-wide association study identifies
a single major locus contributing to survival into
old age; the APOE locus revisited. Aging Cell. 2011 Mar
21. in press.
12. Passtoors W.M., et al., Genomic studies in ageing
research: the need to integrate genetic and gene
expression approaches. J Intern Med 2008 Feb; 263(2):
153-66.
13. Kenyon C.J. The genetics of ageing. Nature 2010 Mar
25; 464(7288): 504-12.
14. Barker D.J. The origins of the developmental origins
theory. J Intern Med 2007 May; 261(5): 412-7.
15. Heijmans B.T., et al., Persistent epigenetic differences
associated with prenatal exposure to famine in
humans. Proc Natl Acad Sci U S A 2008 Nov 4; 105(44):
17046-9.