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Neonatale anesthesie

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Congenitale hernia diafragmatica<br />

• incidentie:1/2000-1/5000<br />

• onvolledig sluiten pleuro-peritoneaal kanaal<br />

• 75%-90% foramen van Bochdalek<br />

• bilatherale vormen 1%, vaak lethaal<br />

• diagnose: polyhydramnios, rx thorax,<br />

antenatale echografie<br />

• mortaliteit: >20%<br />

• prognose afh pulmonale hypoplasie en<br />

geassocieerde congenitale pathologie<br />

• fœtale chirurgie<br />

Congenitale hernia diafragmatica<br />

• kliniek<br />

• stabilisatie periode: - beademd (conventioneel, HFO)<br />

- echo-cardio: systemische druk >pulmonale druk<br />

- episodes hypoxie tgv rechts-links shunt<br />

- gebruik NO (pulm.vasc.hyperreactiviteit)<br />

-ECMO<br />

• chirurgie: direct of met goretex<br />

• <strong>anesthesie</strong>: - NO behouden indien nodig<br />

- conventionele beademing (pvv-ippv)<br />

- barotrauma!<br />

- saturatie meting pre- en postductaal<br />

- intraveneuze lijn bovenste lidmaat!<br />

- lage conc. sevoflurane, geen lachgas<br />

-opioden, ketamine<br />

- caudale catheter<br />

36

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