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scienze della vita roma, 22-23 ottobre 2012 - SIF

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8. Savojardo C, Fariselli P, Alhamdoosh M, Martelli PL, Pierleoni A, Casadio R-Improving the prediction of<br />

disulfide bonds in Eukaryotes with machine learning methods and protein subcellular localization- Bioinformatics<br />

27:<strong>22</strong>24-<strong>22</strong>30 (2011) (*)<br />

9. Piovesan D, Luigi Martelli P, Fariselli P, Zauli A, Rossi I, Casadio R -BAR-PLUS: the Bologna Annotation<br />

Resource Plus for functional and structural annotation of protein sequences- Nucleic Acids Res 39:W197-W202 (2011)<br />

(*)<br />

10. Pierleoni A, Indio V, Savojardo C, Fariselli P, Martelli PL, Casadio R -MemPype: a pipeline for the annotation<br />

of eukaryotic membrane proteins- Nucleic Acids Res 39:W375-W380 (2011) (*)<br />

11. Pantaleo MA, Astolfi A, Indio V, Moore R, Thiessen N, Heinrich MC, Gnocchi C, Santini D, Catena F,<br />

Formica S, Martelli PL, Casadio R, Pession A, Biasco G -SDHA Loss-of-Function Mutations in KIT-PDGFRA Wild-<br />

Type Gastrointestinal St<strong>roma</strong>l Tumors Identified by Massively Parallel Sequencing- J Natl Cancer Inst 103:983-987<br />

(2011) (*)<br />

12. Pierleoni A, Martelli PL, Casadio R -MemLoci: predicting subcellular localization of membrane proteins in<br />

Eukaryotes- Bioinformatics 27:1<strong>22</strong>4-1<strong>23</strong>0 (2011) (*)<br />

PROSPETTIVE ED OBIETTIVI PER I PROSSIMI TRE ANNI<br />

Sviluppo di tools e piattaforme integrate per l’analisi di dati derivanti da sequenziatori di ultimissima generazione. Il<br />

gruppo ha di recente acquisito un ION TORRENT (vedi Genome Biology Group:<br />

www.biocomp.unibo.it/centregenomebio) per varie applicazioni di genetica animale e medica.<br />

COLLABORAZIONI INTERNAZIONALI IN ATTO<br />

1. RGB-Net: a Collaborative European Network on Rabbit Genome Biology<br />

(http://www.biocomp.unibo.it/rabbit/)<br />

2. Prof. David Jones - University College London, Department of Computer Science<br />

(http://www0.cs.ucl.ac.uk/staff/d.jones/)<br />

3. Prof. Hongbin Shen - Department of Automation, Shanghai Jiao Tong University, Shanghai<br />

(http://www.csbio.sjtu.edu.cn/index_Eng.htm)<br />

PRINCIPALI ATTREZZATURE DI CUI DISPONE L’UNITÀ DI RICERCA<br />

i) Cluster high performance: 5 dual Xeon core2 servers, per un totale di 28 processori e 15 TB di capacità di<br />

data storage;<br />

ii) Cluster di 2 servers dual Opteron dual core e 6 server dual xeon;<br />

iii) 2 File servers;<br />

iv) 8 Linux workstation.<br />

PAROLE CHIAVE<br />

LS2_13 Bioinformatics<br />

LS2_14 Computational biology<br />

LS2_16 Systems biology<br />

LS2_9 Proteomics<br />

LS2_8 Genomics, comparative genomics, functional genomics<br />

87

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