pKa's OF DRUGS AND REFERENCE COMPOUNDS A B

Name pKa ReferenceMeclizine 3.1 1186.2Medazepam 6.2 1194.4 7Mefenamic Acid 4.3 74Mepazine 9.3 53Meperidine 8.7 14Mephentermine 10.3 35Mephenytoin 8.1 120Mephobarbital 7.7 85Mepivacaine 7.6 39Mercaptomerin 3.7 425.1Mercaptopurine 7.8 121Metaproterenol 8.8 1511.8 30Metaraminol 8.6 29Methacycline 3.5 157.69.2Methadone 8.3 14Methamphetamine 9.5 43Methapyrilene 3.7 38.9 (side chain)Methaqualone 2.5 122Metharbital 8.2 85Methazolamide 7.3 18Methdilazine 7.5 15Methenamine 4.9 29Methicillin 2.8 19L-Methionine 2.3 329.2Methohexital 8.3 123Methopromazine 9.4 62Methotrexate 4.8 1245.53.8 37Methotrimeprazine 9.2 50Methoxamine 9.2 64Methoxyacetic Acid 3.5 12o-Methoxybenzoic Acid 4.2 38m-Methoxybenzoic Acid 4.2 38o-Methoxycinnamic Acid 4.7 38m-Methoxycinnamic Acid 4.5 38p-Methoxycinnamic Acid 4.9 38Name pKa ReferenceMethyclothiazide 9.4 125Methylamine 10.6 121-Methylbarbituric Acid 4.4 17Methyldopa 2.2 12610.6 (amine)9.2 (1st phenol)12.0 (2nd phenol)N-Methylephedrine 9.3 127Methylergonovine 6.7 81N-Methylglucamine 9.2 126Methylhexylamine 10.5 64Methylparaben 8.4 41Methylphenidate 8.8 128Methylprednisolone-21-phosphate 2.6 1296.0Methylpromazine 9.4 62Methyprylon 12.0 130Methysergide 6.6 81Metolazone 9.7 42Metopon 8.1 14Metoprolol 9.7 15Metronidazole 2.6 131Miconazole 6.9 132Minocycline 2.8 155.07.89.5Molindone 6.9 133Monochloroacetic Acid 2.9 42Morphine 8.0 329.6 (phenol)NNafcillin 2.7 26Nalidixic Acid 6.0 (amine) 1341.0Nalorphine 7.8 14Naloxone 7.9 42Naphazoline 3.9 6410.1 501-Naphthol 9.2 382-Naphthol 9.4 38Naproxen 4.2 135Narcotine 5.9 3Neostigmine 12.0 94