rezistentuli tuberkulozi

7. mkurnaloba7.1. mkurnalobis ZiriTadi principebi• yvela pacientis mkurnalobis uzrunvelyofa xdeba individualurireJimiT meore rigis medikamentebis DST mixedviT. empiriuli reJimisgamoyeneba SesaZlebelia savaraudo DR-TB pacientSi sanam cnobiligaxdeba meore rigis tubsawinaaRmdego medikamentebis DST pasuxi.• medikamentebis TiToeuli dozis miReba rogorc intensiur, isegagrZelebis fazaSi xdeba uSualo meTvalyureobis qveS DOTprincipiT.• zogierTi, Znelad asatani medikamentis miReba iwyeba dabalidozebiT, sasurvel dozamde zrda xdeba 3-10 dRis ganmavlobaSi 2 .• meore rigis medikamentebis maqsimaluri dozebi gamoyenebaSesaZleblobis farglebSi da aqtiuri gverdiTi movlenebismarTvasTan erTad.• mkurnaloba tardeba kviraSi 6 dRe, SesaZlebelia dReSi 2-jer.intermitiuli reJimi ar aris rekomedebuli arc intensiur da arcgagrZelebis fazaSi (gamonaklisia, peroraluri medikamentebi,romlebic SeiZleba dainiSnos kviraSi 3-jer, Tu aRiniSneba iseTigverdiTi movlenebi, rogoricaa mag., Tirkmlebis ukmarisoba).pirveli da meore rigis tubsawinaaRmdego medikamentebisrekomendebuli dozebi ZiriTad gverdiT movlenebTan erTadmoyvanilia cxrilSi #2 da 3.cxrili #2pirveli rigis tubsawinaaRmdego medikamentebis dozebi da gverdiTimovlenebipirveli rigismedikamentebirekomendebuli dRiuridozagverdiTi movlenaizoniazidi 5 mg/kg periferuli neiropaTia, siyviTle,fsiqiuri aSlilobis simptomebi,hipermgrZnobeloba (cxeleba angamonayari kanze)rifampicini 10 mg/kg siyviTle, Trombocitopenia,gripismagvari sindromipirazinamidi 25 mg/kg arTralgia, siyviTleetambutoli 15 mg/kg mxedvelobis nervis nevritistreptomicini 15 mg/kg ototoqsiuroba, nefrotoqsiuroba,hipermgrZnobeloba2 Iseman M. Treatment of multidrug-resistant tuberculosis. New Eng J 1993; 329: 784-791. A / II7