rezistentuli tuberkulozi

• am medikamentebis daniSvnisas daculi unda iyos Semdegi principebi:safexuri IyovelTvis iniSneba saineqcio medikamenti (Km, Cm) Tu arismgrZnobelobasafexuri IIyovelTvis iniSneba FQ (Ofx, Lvx, Mfx) Tu aris mgrZnobelobasafexuri III reJimi ivseba me-4 jgufis II rigis medikamentiT – Pto, PASda/an Cssafexuri IV meore rigis medikamentebis mimarT rezistentobis anautanlobis SemTxvevaSi gamoiyeneba mesame rigis medikamentebi(V jgufi) - amoqsicilini-klavulanis mJava (AmxClv),klofazimini (Cfz), klariTromicini (Clr)(2 III rigis medikamenti = 1 meore rigis medikaments)safexuri Vemateba Z da E, im SemTxvevaSi Tu ar arsebobs rezistentobismtkicebuleba, magram isini ar iTvleba ZiriTad reJimSi.• multirezistentuli tuberkulozis MDR-TB mkurnalobisprincipebis ganmartebebi:meore rigis saineqcio medikamentebi (II jgufi):saineqcio medikamenti (II jgufi) yovelTvis Sedis mkurnalobis reJimSi(im varaudiT, rom arsebobs mgrZnobeloba sami aseTi medikamentidanerT-erTze mainc) da keTdeba yoveldRiurad, minimum 6 dRe kviraSisanam ar moxdeba kulturaluri konversia, sul mcire 6 TvisganmavlobaSi.ftorqinolonebi (III jgufi):ftorqinoloni gamoiyeneba yvela SemTxvevaSi, rodesac arismgrZnobeloba.dResaTvis, yvelaze Zlieri qinolonebi, klebiTi TanmimdevrobiT, arian:moqsifloqsacini = gatifloqsacini > levofloqsacini > ofloqsacini= ciprofloqsacini 4 .monacemebi moqsifloqsacinisa da gatifloqsacinis xangrZlivi damaRali dozebis (>400mg/dReSi) gamoyenebis usafrTxoebis Sesaxeb,Zalian mwiria. 54 WHO. Draft Guidelines for Drug Resistant TB, April 20055 American Thoracic Society, CDC, and Infectious Diseases Society of America. MMWR.14