rezistentuli tuberkulozi

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SesaZloa gamoyenebul iqnen MDR-TB pacientebSi, meore rigismedikamentebis mimarT rezistentobis an autanlobis SemTxvevaSi.V jgufiMedikamenti gverdiTi movlenebi dozaklofaziminiklofaziminis kafsul.BP2000,amoqsicilini/klavulinatinhibitoriklariTromicini- doza damokidebuli: kanis wiTelian yavisferi Seferva mzissxivebis moqmedebiT. Tmis,cremlis, oflis, naxvelis, rZis,Sardis Seferva.- darRvevebi kuW-nawlavis traqtismxriv- wvrili nawlavis kedlebSi,mezenteriul limfur kvanZebSi dasxva organoebSi kristalebisCalageba.- kanis simSrale, iqtiozi, qavili,fotomgrZnobeloba.- Tavistkivili, gabrueba,gemovnebis moSla- darRvevebi kuW-nawlavis traqtismxriv- alergiuli reaqciebi- hepatiti- qolestazuri siyviTle- eqsfoliaciuri dermatiti,toqsikuri epidermuli nekrolizi- darRvevebi kuWnawlavis traqtismxriv- gemovnebis moSla, stomatiti,glositi da kbilebis Seferva- RviZlis fermentebis xanmoklemomatebis epizodebi,qolestazuri siyviTle, hepatiti- cns-is mxriv gardamavalixasiaTis movlenebi:- smenis daqveiTeba (Seqcevadi)- hipoglikemia- Trombocitopeniuri purpura- fsevdomembranuli koliti- QT intervalis gaxangrZliveba- intersticiuli nefritiTirkmlis ukmarisobacxrili #43abi/dR 1 an ormiRebaze uSualodsakvebis Semdeg.875/125 2XdR, 1abiklavulinati+ 1,5abi amoqsicilini2abi/dR, 1-2miRebaze.pediatriaSi:7,5mg/kg 2X dR7.2. empiriuli mkurnaloba (ETR)ETR gamoiyeneba rezistentul tuberkulozze mniSvnelovani eWvisSemTxvevaSi (cxrili #5). aseT mkurnalobas Tavazoben pacients,romelsac aqvs MDR-TB diagnozis maRali riski, rom ar daikargos droda Tavidan iqnas acilebuli rezistentobis gaZliereba.empiriuli mkurnaloba iniSneba Semdeg SemTxvevebSi:10
- axlo kontaqti MDR-TB pacientTan (ojaxis wevrebi);- pirveli rigis medikamentebiT mkurnalobis uSedego gamosavlisas(kulturiT dadasturebuli), rodesac DST pirveli rigismedikamentebis mimarT jer ar aris cnobili;- DST Sedegebi pirveli rigis medikamentebis mimarT cnobilia davelodebiT DST-s meore rigis medikamentebis mimarT.ETR Cvenebebicxrili #5uSedego kategoria kontaqti MDR-TB-Tankargi klinikurimdgomareoba- gaigzavnos DST- davucadoT saboloo- gaigzavnos DST- ETR*DST Sedegs sanamdaiwyeba ITRmZime klinikurimdgomareoba- gaigzavnos DST- ETR- gaigzavnos DST- ETR** gamoiyeneba konkretuli SemTxvevis DST wamlebis asarCevad + HR.MDR-TB pacientTan axlo kontaqtSi myofi pirebisTvis ETR SedgebaSemdegi medikamentebisgan: H - R - Z - Cm / Ofx / PAS ( an Cs) / Pto (HRZ + 4meore rigis medikamenti), H da R grZeldeba DST Sedegebis miRebamde.empiriuli mkurnalobis intensiuri faza, rodesac cnobilia DSTpirveli rigis medikamentebis mimarT, Cveulebriv Sedgeba Semdegimedikamentebisgan: Cm (an Km) +Fq +Eto + PAS + Cs + Z (Z + 5 meore rigismedikamenti), sanam cnobili gaxdeba meore rigis medikamentebis mimarTmgrZnobelobis testis Sedegi, rom daiwyos individualurimkurnaloba.7.3. mono da polirezistentuli tuberkulozis (PDR-TB)SemTxvevaTa marTvamono da polirezistentuli tuberkulozis mkurnaloba efuZnebaSemdgom sqemebs:sqema A.iniSneba H an HS rezistentobis SemTxvevaSiTu gamovlinda H rezistentoba I an II kategoriis intensiuri fazisdasrulebamde, unda Sewydes H–is gamoyeneba intensiuri fazisbolomde; Semdeg, im varaudiT, rom pacienti gaxda kultura-uaryofiTi,dainiSnos gagrZelebis faza 7 TviT (mag., 7REZ), rom Sesruldesmkurnalobis sruli kursis minimum 9 Tve. Tu pacienti kidev kulturadadebiTiamkurnalobis dawyebidan 2 Tvis Semdeg da DST Sedegi aricvleba*, grZeldeba adaptaciuri reJimiT mkurnaloba kulturiskonversiamde (kultura-uaryofiTad); mas Semdeg rac moxdeba konversia,11
Page 4 and 5: The schools who have or will receiv
Page 6 and 7: ganisazRvreba: MGIT swrafi meTodiT
Page 8 and 9: cxrili #3meore rigis medikamentebi,
Page 12 and 13: pacienti iwyebs gagrZelebis fazas 7
Page 14 and 15: • am medikamentebis daniSvnisas d
Page 16 and 17: E da Z mimarT mgrZnobelobis SemTxve
Page 18 and 19: aseT SemTxvevebSi saukeTesoa samkur
Page 20 and 21: exmareba eqTans am samuSaos Sesrule
Page 22 and 23: TionamidebieTionamidi(Eto)proTionam
Page 24 and 25: amoqsicilini/klavulinismJavaklariTr

rezistentuli tuberkulozi

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