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Azienda Ospedaliera Nazionale“SS. Antonio e Biagio e Cesare Arrigo”Working Paper of Public Healthnr. 18/2012Figura 1 Probabilità di sopravvivenza libera da recidiva10090Relapse Free Survival probability (%)807060504030201000 12 24 36 48 60 72 84 96 108 120 132 144 156 168 180monthsNumber at risk117 104 89 64 47 37 28 20 14 6 3 3 1 0AuthorTabella 3 Casistiche di tumori del retto pretrattati sottoposti a chirurgia mininvasivayear N o pts Perspective Conversion PathologicalPretreatedRate (%) responsereportedMeanFollow up(mos)Bärlehner et al 2005 120 No 14* no 18 * 89%* 1.4%*Lujan et al 2009 73 Yes 7.9* no 32.8* 72.1%* 4.8%*Pugliese et al 2009 48 No 9.5* yes 48 * 73.7%* 4.1%*Staudacher et al] 2007 109 No 6.1* yes 39.8* 81%* 6.1%*Kang et al 2010 170 Yes 1.2 yes - - -Baek et al] 2010 54 No 9.2* no 20.2* 96.2%* 3.1%*Marks et al 2010 79 No 2.5 yes 34.2 97% 2.7%Soumarova et al 2010 78 Yes 17 yes - - -Cone et al 2011 50 No 26 yes 33.7 - 9.6%Sartori et al 2011 68 No 4.6* no 48.6* 75.4%* 3.44%*Grosso et al 2011 117 No 8 yes 52 76.5% 6.8%Legenda: OS overall survival; LR local relapse*data related to pre-treated and untreated patientOSLR17
Azienda Ospedaliera Nazionale“SS. Antonio e Biagio e Cesare Arrigo”Working Paper of Public Healthnr. 18/2012Conflitto di interessiNessuno degli autori dichiara alcun conflitto di interessi relativo a questo manoscritto.Informazioni sugli autoriGiuseppe Spinoglio è il Direttore del Dipartimento di Chirurgia presso l’Azienda Ospedaliera“SS Antonio e Biagio”. Egli è particolarmente esperto della chirurgia miniinvasiva essendouno dei membri fondatori dell'Associazione Internazionale di Chirurgia Robotica Clinica.RiconoscimentiQuesto studio è dedicato ai nostri pazienti ed ai loro familiari che, ogni giorno, con la lorosofferenza, ci insegnano la difficile arte della medicina.Riferimenti1. Carlsen E, Schlichting E, Guldvog I, Johnson E, Heald RJ: Effect of the introductionof total mesorectal excision for the treatment of rectal cancer. Br J Surg, 85:526-9,1998.2. Rullier E, Zerbib F, Laurent C, Bonnel C, Caudry M, Saric J, Parneix M.Intersphincteric resection with excision of internal anal sphincter for conservativetreatment of very low rectal cancer. Dis Colon Rectum, 42:1168-75, 1999.3. Marks J, Mizrahi B, Dalane S, Nweze I, Marks G. Laparoscopic transanal abdominaltransanal resection with sphincter preservation for rectal cancer in the distal 3 cm ofthe rectum after neoadjuvant therapy. Surg Endosc, 24:2700-7, 2010.4. Buunen M, Bonjer HJ, Hop WC, Haglind E, Kurlberg G, Rosenberg J, Lacy AM,Cuesta MA, D'Hoore A, Fürst A, Lange JF, Jess P, Bulut O, Poornoroozy P, Jensen18
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