Working Paper of Public Health Volume 2012 - Azienda Ospedaliera ...

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Azienda Ospedaliera Nazionale“SS. Antonio e Biagio e Cesare Arrigo”Working Paper of Public Healthnr. 18/2012Tabella 1 Caratteristiche dei pazienti e dettagli dei trattamentiPATIENTS CHARACTERISTICSSexF No (%)M No (%)Age, yearsMedianRangePS (ECOG)01Location of the tumourUpper (≥ 12 -
Azienda Ospedaliera Nazionale“SS. Antonio e Biagio e Cesare Arrigo”Working Paper of Public Healthnr. 18/2012Time between surgery and adjuvant CT startMedianRangeIQR3826-6332-43Legenda CT: Chemotherapy; RT: Radiotherapy; 5FU: 5-Fluorouracil; CAP: Capecitabine; LOHP: Oxaliplatin;FOLFOX: 5FU plus Oxaliplatin;, Xelox: Capecitabine plus Oxaliplatin; Degramont: 5FU bolus and continuousinfusionTabella 2 Esiti di trattamentoTREATMENT OUTCOMESPathological stageStage 0 (yp T0; ypN0)Stage I (yp T1-T2; yp N0)Stage IIA (yp T3; yp N0)Stage IIIA (yp T1-T2; yp N1)Stage IIIB (yp T2-T3; yp N2)Stage IV (anyT,anyN, M1)Distal marginmeanrangeMandard Tumor Regression GradeTRG1TRG2TRG3TRG4TRG5Downstaging clinical/pathologicalYesNoRelapseLocalLocal + DistantDistantMetastatic sitesLungLiverLung + liverCNSOther5-year OutcomesRFSLRFSDRFSOS18 (16% )40 (34%)35 (30%)6 ( 5%)15 (13%)3 ( 2%)3,5 cm1-10 cm9718 (20%)15 (15%)13 (13%)37 (38%)14 (14%)70 (66%)47 (34%)1 ( 2%)7 ( 5%)16 (13%)12 (54%)3 (14%)2 ( 9%)1 ( 5%)4 (18%)% (90%CI)76,5 65,6-84,294 87,1-97,974,2 62,8-84,277,5 66,9-86,1Legenda: TRG: tumor regression grade; RFS: Relapse free survival; LRFS: Local Relapse free survival;DRFS:Distant Relapse free survival; OS: Overall survival; CNS: central nervous system16
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