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Azienda Ospedaliera Nazionale“SS. Antonio e Biagio e Cesare Arrigo”Working Paper of Public Healthnr. 15/2012Si può allora concludere che l’utilizzo di più marcatori associati e un’anamnesi appropriatasono indispensabili per l’interpretazione dei singoli casi e per la corretta formulazione delladiagnosi nei diversi aspetti dell’abuso alcolico.BIBLIOGRAFIAAllen JP, Litten RZ. (2003) Recommendations in use of biomarkers in alcoholism treatmenttrials. Alcohol Clin Exp Res 27: 1667-70Alling C, Chick JD, Anton R, et al. (2005) Revealing alcohol abuse: to ask or to test.Alcohol Clin Exp Res 29:1257-63.Aradottir S, Olsson BL. (2005) Methodologic modifications on quantification ofphosphatidylethanol in blood from humans abusing alcohol, using high-performance liquidchromatography and evaporative light scattering. BMC Biochem 6: 18.Aradottir S, Asanovska G, Gjerss S, et al. (2006) Phosphatidylethanol (PEth) concentrationsin blood are correlated to reported alcohol intake in alcohol-dependent patients. AlcoholAlcohol 41: 431-37.Bianchi V (2006). Transferrina carboidrato carente: nuovo marcatore di abuso alcolico. 1rded. Turin: Ananke.Bianchi V, Raspagni A, Arfini A.(2008) Vecchi e nuovi marcatori di abuso alcolico nellematrici biologiche. 1rd ed. Turin: AnankeBianchi V, Arfini C, Helander A. (2008a) Determination of carbohydrate-deficient transferrin(CDT) in Italy, Clin Chem Lab Med 46: 2759-62.Bianchi V, Piccinini S, Raspagni A, et al. (2009) Test immunoenzimatico per il dosaggio infase omogenea per il dosaggio dell’etilglucuronide nelle urina Minerva Med Leg 129: 177-82.Bianchi V, Ivaldi A, Raspagni A, Arfini C, Vidali. M. (2010) Carbohydrate-deficienttransferrin (CDT) alone and combinated with GGT ( γ-CDT) in traffic medicine AlcoholAlcohol 3: 306-11Bianchi V, Ivaldi A, Raspagni A, et al. (2011) Pregnancy and variations of carbohydratedeficienttransferrin levels measured by the candidate reference HPLC method. AlcoholAlcohol 46: 123 –7.17
Azienda Ospedaliera Nazionale“SS. Antonio e Biagio e Cesare Arrigo”Working Paper of Public Healthnr. 15/2012Bianchi V, Ivaldi A , Raspagni A, et al. (2012) High-performance liquid chromatographyevaluation of serum carbohydrate-deficient transferrin and more sialylated transferringlycoforms in children. Scand J Clin Lab Invest 72: 274-8.Bakdash A, Burger P, Goecke TW, et al. (2010) Quantification of fatty acid ethyl esters(FAEE) and ethyl glucuronide (EtG) in meconium from newborns for detection of alcoholabuse in a maternal health evaluation study.Anal Bioanal Chem 396: 2469-77.Bird DA, Laposata M, Hamilton JA. (1996) Binding of ethyl oleate to low densitylipoprotein, phospholipid vesicles and albumin: a 13C NMR study. J Lipid Res 37: 1449-58.Borucki K, Dierkers J, Warteberg J, et al. (2007) In heavy drinkers, fatty acid ethyl estersremain elevated for up to 99 hours. Alcohol Clin Exp Res 31: 423-7.Crivellente F, Fracasso G, Valentini R, et al. (2000) Improved method for carbohydratedeficienttransferrin determination in human serum by capillary zone electrophoresis. JChromatogr B 739: 81-93.Diczfalusy MA, Bjorkhem I, Einarsson C, et al. (2001) Characterization of enzymes involvedin formation of ethyl esters of long-chain fatty acids in humans. J Lipid Res 42: 1025-32.Doyle KM, Cluette-Brown JE, Dube DM, et al. (1996) Fatty Acid ethyl esters in the blood asmarkers for ethanol intake. JAMA 276: 1152-6.Gunnarsson T, Karlsson A, Hansson P, et al. (1998) Determination of phosphatidylethanol inblood from alcoholic males using high-performance liquid chromatography and evaporativelight scattering or electrospray mass spectrometric detection. J Chromatogr B Biomed SciApp 705: 243-9.Gustavsson L, Allig C. (1987) Blood phosphatidylethanol in rat brain by phospholipidae D.Bioch Biophys Res Comm 142: 958-63.Hannuksela ML, Liisanantii MK, Savolainen MJ. (2003) Effect of alcohol on lipids andlipoproteins in relation to atherosclerosis. Crit Rev Clin Lab Sci 39: 225-83.Hasaba A, LaposataM. (2001)The synthesis and secretion of fatty acid ethyl esthers fromHepG2 cells are stimulated by lipoproteins and albumin. Alcohol Clin Exp Res 25: 338-43.Helander A, Husa A, Jeppsson JO. (2003) Improved HPLC method for carbohydratedeficienttransferrin in serum. Clin Chem 9: 1881-90.Helander A, Beck O. (2004) Mass spectrometric identification of ethyl sulphate as an ethanolmetabolite in humans. Clin Chem 50: 936-7.Helander A, Olsson I, Dahl H . (2007) Postcollection syntesis of ethyl glucuronide bybacteria in urine may cause false identification of alcohol consumption. Clin Chem 53: 1-3.18
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