sul tromboembolismo venoso - Supplements - Haematologica
sul tromboembolismo venoso - Supplements - Haematologica
sul tromboembolismo venoso - Supplements - Haematologica
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20<br />
Società Italiana per lo Studio dell’Emostasi e della Trombosi<br />
esame strumentale (in prima<br />
battuta l’ecografia).<br />
La combinazione di probabilità<br />
clinica, US e D-dimeri è raccomandata<br />
nell’approccio diagnostico<br />
alla TVP (vedi allegati<br />
1,2,3).<br />
L’ecografia rappresenta l’esame<br />
di prima scelta per la diagnosi<br />
di trombosi venosa dell’arto<br />
superiore. La flebografia<br />
può trovare indicazione nei casi<br />
dubbi.<br />
La diagnosi definitiva di trombosi<br />
cavale si deve basare su<br />
angio-TC o RM, particolarmente<br />
indicate in presenza di malattia<br />
neoplastica.<br />
L’eco-color-doppler può essere<br />
considerato utile quale primo<br />
esame, soprattutto in presenza<br />
di TVP degli arti inferiori, ma un<br />
esito normale non esclude la<br />
diagnosi, soprattutto in presenza<br />
di un forte sospetto clinico.<br />
L’uso della cavografia dovrebbe<br />
essere limitata al planning<br />
chirurgico, in assenza di adeguata<br />
strumentazione TC o RM.<br />
Pur in assenza di studi di confronto<br />
con altre metodiche, la<br />
RM è il test diagnostico raccomandato<br />
per la diagnosi di<br />
trombosi venosa cerebrale.<br />
L’ecografia rappresenta il test<br />
di primo impiego per la diagnosi<br />
di trombosi portale. La TC e<br />
l’angiografia portale sono metodiche<br />
di approfondimento.<br />
Bibliografia<br />
1. Buller HR, Lensing AWA, Hirsh J, Tencate JW. Deep<br />
vein thrombosis - new non-invasive diagnostic tests.<br />
Thromb Haemost 1991;66:133-7.<br />
2. Hirsh J. Antithrombotic Therapy in Deep Vein<br />
Thrombosis and Pulmonary Embolism. Am Heart J<br />
1992;123: 1115-22.<br />
3. Kakkar VV. Venous thrombosis today. Haemostasis<br />
1994;24:86-104.<br />
4. Cogo A, Lensing AWA, Prandoni P, Hirsh J. Distribution<br />
of thrombosis in patients with symptomatic<br />
deep vein thrombosis - implications for simplifying<br />
the diagnostic process with compression ultrasound.<br />
Arch Intern Med 1993;153:2777-80.<br />
5. Wells PS, Anderson DR, Bormanis J, Guy F, Mitchell<br />
M, Gray L, et al. Value of assessment of pretest probability<br />
of deep-vein thrombosis in clinical management.<br />
Lancet 1997;350:1795-8.<br />
6. Miron MJ, Perrier A, Bounameaux H. Clinical assessment<br />
of suspected deep vein thrombosis: comparison<br />
between a score and empirical assessment. J<br />
Intern Med 2000;247:249-54.<br />
7. Lensing AWA, Buller HR, Prandoni P, Batchelor D,<br />
Molenaar AHM, Cogo A, et al. Contrast venography,<br />
the gold standard for the diagnosis of deep-vein<br />
thrombosis - improvement in observer agreement.<br />
Thromb Haemost 1992;67:8-12.<br />
8. Hull RD, Feldstein W, Pineo GF, Raskob GE. Cost<br />
effectiveness of diagnosis of deep vein thrombosis<br />
in symptomatic patients. Thromb Haemost<br />
1995;74:189-96.<br />
9. Lensing AWA, Prandoni P, Brandjes D, Huisman PM,<br />
Vigo M, Tomasella G, et al. Detection of deep-vein<br />
thrombosis by real-time B-mode ultrasonography. N<br />
Engl J Med 1989;320:342-5.<br />
10. Kearon C, Julian JA, Newman TE, Ginsberg JS. Noninvasive<br />
diagnosis of deep venous thrombosis.<br />
McMaster diagnostic imaging practice guidelines initiative.<br />
Ann Intern Med 1998;128:663-77.<br />
11. Elias A, Mallard L, Elias M, Alquier C, Guidolin F,<br />
Gauthier B, et al. A single complete ultrasound investigation<br />
of the venous network for the diagnostic<br />
management of patients with a clinically suspected<br />
first episode of deep venous thrombosis of the lower<br />
limbs. Thromb Haemost 2003;89:221-7.<br />
12. Schellong SM, Schwarz T, Halbritter K, Beyer J,<br />
Siegert G, Oettler W, et al. Complete compression<br />
ultrasonography of the leg veins as a single test for<br />
the diagnosis of deep vein thrombosis. A prospective<br />
clinical outcome study. Thromb Haemost<br />
2003;89:228-34.<br />
13. Ginsberg JS, Wells PS, Hirsh J, Panju AA, Patel MA,<br />
Malone DE, et al. Reevaluation of the sensitivity of<br />
impedance plethysmography for the detection of<br />
proximal deep vein thrombosis. Arch Intern Med<br />
1994;154:1930-3.<br />
14. Robinson BJ, Kesteven PJL, Elliott ST. The role of<br />
strain gauge plethysmography in the assessment of<br />
patients with suspected deep vein thrombosis. Br J<br />
Haematol 2002; 118:600-3.<br />
15. Maskell NA, Cooke S, Jones DJM, Prior JG, Butland<br />
RJA. The use of automated strain gauge plethysmography<br />
in the diagnosis of deep vein thrombosis.<br />
Br J Radiol 2002;75:648-51.<br />
16. Kahn SR, Joseph L, Grover SA, Leclerc JR. A randomized<br />
management study of impedance plethysmography<br />
vs. contrast venography in patients with<br />
a first episode of clinically suspected deep vein<br />
thrombosis. Thromb Res 2001;102:15-24.<br />
17. Indik JH, Alpert JS. Detection of pulmonary<br />
embolism by D-Dimer assay, spiral computed tomography,<br />
and magnetic resonance imaging. Prog Cardiovasc<br />
Dis 2000; 42:261-72.<br />
18. Loud PA, Katz DS, Klippenstein DL, Shah RD, Grossman<br />
ZD. Combined CT venography and pulmonary<br />
angiography in suspected thromboembolic disease:<br />
Diagnostic accuracy for deep venous evaluation. Am<br />
J Roentgenol 2000;174:61-5.<br />
19. Garg K, Kemp JL, Wojcik D, Hoehn S, Johnston RJ,<br />
Macey LC, et al. Thromboembolic disease: Comparison<br />
of combined CT pulmonary angiography and<br />
venography with bilateral leg sonography in 70<br />
patients. Am J Roentgenol 2000;175:997-1001.<br />
20. Maki DD, Kumar N, Nguyen B, Langer JE, Miller WT,<br />
Gefter WB. Distribution of thrombi in acute lower<br />
extremity deep venous thrombosis: Implications for<br />
sonography and CT and MR venography. Am J<br />
haematologica vol. 88[supplement 18]: December 2003