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Processi che coinvolgono la chemochine e i loro recettori

Processi che coinvolgono la chemochine e i loro recettori

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Differenziazione Th1 e Th2<br />

Patogeni intracellu<strong>la</strong>ri<br />

CCL3+<br />

CCL4+<br />

CCL5+<br />

Th1<br />

CCR5+<br />

CXCR3+<br />

CCR7<br />

produzione IFN-γ<br />

IP-10<br />

Mig<br />

MIP-1β<br />

T helper<br />

CCL2+<br />

Altri meccanismi<br />

MDC<br />

TARC<br />

TCA-3<br />

Patogeni extracellu<strong>la</strong>ri<br />

Th2<br />

CCR4+<br />

CCR8+<br />

CCR2+<br />

CCR7<br />

produzione<br />

IL-4 e IL-13<br />

S.A. Luther et al., Chemokine as regu<strong>la</strong>tors of T cell differentiation, Nature immunology, 2: 102-107,2001

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