aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ... aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
damateba 5. mkurnalobis reJimis dacvis monitoringis meTodebi TviT-angariSi kargi markeria mkurnalobis reJimisa, magram ara saukeTeso. igi gadaWarbebulad afasebs arT-s efeqturobas, vidre sxva meTodi (128). aucilebelia pacientma gaamJRavnos problemebi pirispir saubrisas. es meTodi SeiZleba iyos mniSvnelovani pacientis rolis gaZlierebisTvis mkurnalobis dagegmvaSi, sapirispirod mowodebuli kontrolirebadi meTodisa. momwodeblis Sefaseba mwiria (129) da ar aris sasurveli. wamlis donis monitoringi aris Zviri da SeuZlebelia yvela arT-ze myofi pacientisTvis. es ar aris rutinuli meTodi mkurnalobis efeqturobis kontrolisTvis. im SemTxvevaSi, rodesac plazmaSi wamlis Semcveloba dabalia, mkurnalobis efeqturoba ar ganixileba. plazmaSi wamlis done aris laboratoriuli markeri , romelic aCvenebs mag. zidovudinis miRebis reJimis dacvas. samedicino SemTxvevebis monitoringis sistema (MEMS) xSirad gamoiyeneba kvlevebis dros. tabletebis raodenoba da farmakologiuri dokumenti SeiZleba ganxilul iqnas, rogorc arasasurveli mcdeloba jandacvis muSakebis mxridan akontrolon mkurnalobaze damyoloba. amitom pacients unda movTxovoT, rom Tan hqondes darCenili medikamentebi. tabletebis identifikaciis testi (PIT) warmoadgens axal meTods, romelic korelaciaSia TviTangariSTan (132). pacientebs unda SeeZloT im tabletebis amocnoba, romlebsac Rebuloben (132). pacientebma unda amoarCion is tabletebi, romlebsac Rebuloben sxva msgavsi magram ara identuri arv “tyupi tabletebisgan”. surogati markerebis gamoyeneba realuria, magram dagvianebulia rodesac saxezea miRebis reJimis darRveva. pi-s Semcvel reJimebze ganviTarebuli virusuli araefeqturoba dakavSirebulia miRebis reJimis darRvevasTan da pi-ze genotipuri rezistentobis ararsebobasTan, rac miuTiTebs rom mkurnalobis araefeqturoba gamowveulia reJimis darRveviT (133,134). mimwodeblebi Zalian frTxilad unda iyvnen am markerebis interpretaciisas da gaiTvaliswinon medikamentebis sisxlSi dabali donis sxva SesaZlo mizezebi (131). 62
damateba 6. antiretrovirusuli medikamentebis CamonaTvali cxrili 18 antiretrovirusuli medikamentebis CamonaTvali saerTaSoriso saxeli (INN) nrti abakaviri (ABC) didanozini (ddI) emtricitabini (FTC) lamivudini (3TC) mwarmoeblis saxeli epzikomi US, Kivexa United Kingdom (lamivudini/abakaviri) triziviri Europe, United Kingdom, US (zidovudini/lamivudini/abakaviri) ziageni United Kingdom, United States abaviri viroli viroli LZ (abkaviri/lamivudini/zidovudini) videqsi, videqsi EC dineqsi EC odiviri Kit (didanozini/lamivudini/efavirenzi) aviro-Z virozini viro-Z diviri atripla (efavirenzi/emtricitabini/tenofoviri) emtriva truvada (tenofoviri/emtricitabini) kombiviri United Kingdom, United States (lamivudini/zidovuni) epiviri United Kingdom, United States, zefiqsi United Kingdom epzikomi United Kingdom, kiveqsa United Kingdom (lamivudini/abakaviri) triziviri United Kingdom, United States (zidovudini/lamivudini/abakaviri) lamivoqsi staveqsi-L (lamivudini/stavudini) staveqsi-LN (lamivudini/nevirapini/stavudini) zidoveqsi-L (lamivudini/zidovudini) zidoveqsi-LN (lamivudini/nevirapini/zidovudini) duoviri (lamivudini/zidovudini) duoviri-N (lamivudini/nevirapini/zidovudini) lamiviri odiviri Kit (didanozini/lamivudini/efavirenzi) triomuni (lamivudini/nevirapini/stavudini) heptaviri lamistari 30, lamistari 40 (lamivudini/stavudini) nevilasti (lamivudini/nevirapini/stavudini) zidolami (lamivudini/zidovudini) virolami virokombi (lamivudini/zidovudini) virolansi (lamivudini/nevirapini/stavudini) virolisi (lamivudini/stavudini) virol LZ, abak-ALZ (abkaviri/lamivudini/zidovudini) farmaceptuli kompania GlaxoSmithKline Genixpharma Ranbaxy Bristol-Myers Squibb Ranbaxy (India) Thai Government Bristol-Myers Squibb Cipla GlaxoSmithKline Aurobindo Cipla Genixpharma Ranbaxy 63
- Page 11 and 12: 1.daavadebis definicia Sidsi abrevi
- Page 13 and 14: Sidsi registrirebulia msoflios 216
- Page 15 and 16: egistrirebul SemTxveevaTa 79% saqar
- Page 17 and 18: adamianis imunodeficitis virusis sa
- Page 19 and 20: aiv rnm-is koncentracia plazmaSi mk
- Page 21 and 22: SeuZlebelia da gadamwyveti misi dia
- Page 23 and 24: persistuli generalizebuli limfadeno
- Page 25 and 26: signalis amplifikacia komplementuri
- Page 27 and 28: • vizitamde rezistentobis testis
- Page 29 and 30: • adamianis papilomavirusi (maxvi
- Page 31 and 32: etinitis identifikaciisTvis, rodesa
- Page 33 and 34: cxrili 8 rekomendaciebi arT dawyebi
- Page 35 and 36: arv medikamentebi arseboben Semdegi
- Page 37 and 38: aCveneben, rom pirveladi rezistento
- Page 39 and 40: - tabletebis Cveneba pacientisTvis
- Page 41 and 42: - aqedan gamomdinare, nrti+anrti re
- Page 43 and 44: igulisxmeba im medikamentebis kombi
- Page 45 and 46: X (arv): testebi, romlebic unda Cat
- Page 47 and 48: maRali mgrZnobeloba abakaviri (ABC
- Page 49 and 50: transaminazebis elevacia anrti (all
- Page 51 and 52: ARV toqsiuroba menejmenti nefrotoqs
- Page 53 and 54: xSiri oportonistuli infeqciebia, ma
- Page 55 and 56: cxrilebis wakiTxvis magaliTi 1. cxr
- Page 57 and 58: damateba2. jandacvis msoflio organi
- Page 59 and 60: damateba 4. ZiriTadi informacia ant
- Page 64 and 65: saerTaSoriso saxeli stavudini (d4T)
- Page 66 and 67: mcire mutacia muSaobs kombinaciaSi.
- Page 68 and 69: 25. Phillips AN et al. Viral load o
- Page 70 and 71: Suppl 2:S171-176. 73. Altice FL, Mo
- Page 72 and 73: 122. Koval CE et al. Immune reconst
- Page 74 and 75: kandidozi dRe yovel dRe - ko-trimoq
- Page 76 and 77: karcinoma (ara SidsTan perikardiuli
- Page 78 and 79: o cxeleba o wonaSi kleba o Ramis of
- Page 80 and 81: indikatorebi filtvis darRveuli funq
- Page 82 and 83: o yvelaze xSirad viTardeba diarea,
- Page 84 and 85: o glukokortikoidebis sistematiuri m
- Page 86 and 87: 100 mg/dReSi meore rigis sqemebi am
- Page 88 and 89: o eqspoziciis Sedegad daavadebis ga
- Page 90 and 91: o remisiis miRweva Zalian Znelia da
- Page 92 and 93: qimioTerapiiT (mag : B-ALL reJimi)
- Page 94 and 95: • imunodeficitis mqone pacientebS
- Page 96 and 97: an famcikloviri 500 mg 3-jer dReSi
- Page 98 and 99: • berkitis-tipis limfoma; • naz
- Page 100 and 101: 3.2.2. cxeleba aiv inficirebulebSi
- Page 102 and 103: afTozuri wylulebi stomatiti qeiliti
- Page 104 and 105: ganmavlobaSi 2 Tvis manZilze (xelis
- Page 106 and 107: o gamonayari warmodgenilia mravlobi
- Page 108 and 109: 20. Chen XM et al. Cryptosporidiosi
- Page 110 and 111: Tavi IV. aiv infeqcia/SidsiT daavad
<strong>da</strong>mateba 6. antiretrovirusuli medikamentebis CamonaTvali<br />
cxrili 18<br />
antiretrovirusuli medikamentebis CamonaTvali<br />
saerTaSoriso<br />
saxeli (INN)<br />
nrti<br />
abakaviri (ABC)<br />
di<strong>da</strong>nozini (ddI)<br />
emtricitabini<br />
(FTC)<br />
lamivudini (3TC)<br />
mwarmoeblis saxeli<br />
epzikomi US, Kivexa United Kingdom<br />
(lamivudini/abakaviri)<br />
triziviri Europe, United Kingdom, US<br />
(zidovudini/lamivudini/abakaviri)<br />
ziageni United Kingdom, United States<br />
abaviri<br />
viroli<br />
viroli LZ (abkaviri/lamivudini/zidovudini)<br />
videqsi, videqsi EC<br />
dineqsi EC<br />
odiviri Kit (di<strong>da</strong>nozini/lamivudini/efavirenzi)<br />
aviro-Z<br />
virozini<br />
viro-Z<br />
diviri<br />
atripla (efavirenzi/emtricitabini/tenofoviri)<br />
emtriva<br />
truva<strong>da</strong> (tenofoviri/emtricitabini)<br />
kombiviri United Kingdom, United States<br />
(lamivudini/zidovuni)<br />
epiviri United Kingdom, United States, zefiqsi<br />
United Kingdom<br />
epzikomi United Kingdom, kiveqsa United Kingdom<br />
(lamivudini/abakaviri)<br />
triziviri United Kingdom, United States<br />
(zidovudini/lamivudini/abakaviri)<br />
lamivoqsi<br />
staveqsi-L (lamivudini/stavudini)<br />
staveqsi-LN (lamivudini/nevirapini/stavudini)<br />
zidoveqsi-L (lamivudini/zidovudini)<br />
zidoveqsi-LN (lamivudini/nevirapini/zidovudini)<br />
duoviri (lamivudini/zidovudini)<br />
duoviri-N (lamivudini/nevirapini/zidovudini)<br />
lamiviri<br />
odiviri Kit (di<strong>da</strong>nozini/lamivudini/efavirenzi)<br />
triomuni (lamivudini/nevirapini/stavudini)<br />
heptaviri<br />
lamistari 30, lamistari 40 (lamivudini/stavudini)<br />
nevilasti (lamivudini/nevirapini/stavudini)<br />
zidolami (lamivudini/zidovudini)<br />
virolami<br />
virokombi (lamivudini/zidovudini)<br />
virolansi (lamivudini/nevirapini/stavudini)<br />
virolisi (lamivudini/stavudini)<br />
virol LZ, abak-ALZ (abkaviri/lamivudini/zidovudini)<br />
farmaceptuli<br />
kompania<br />
GlaxoSmithKline<br />
Genixpharma<br />
Ranbaxy<br />
Bristol-Myers Squibb<br />
Ranbaxy (India)<br />
Thai Government<br />
Bristol-Myers Squibb<br />
Cipla<br />
GlaxoSmithKline<br />
Aurobindo<br />
Cipla<br />
Genixpharma<br />
Ranbaxy<br />
63
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