aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ... aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
hiperbilirubinemia atazanaviri (ATV) >indinaviri ( IDV) o o bilirubinis momateba (SesaZlebelia qavili, araprolongirebuli RviZlis dazianeba, Seqcevadi xSiria o o lovastatini) bilirubinis da klinikuri simtomebis monitoringi wamlebis Sewyveta Tu ar aris tolerantoba. Seicvalos pi. nefroliTiazi indinaviri (IDV) o muclis tkivili, hematuria, Tirkmlis kolika o 10-20% o o Sardis analizis da kreatininis monitoringi mkurnaloba igivea rac nefroliTiazis dros 50
ARV toqsiuroba menejmenti nefrotoqsiuroba tenofoviri TDF o Tirkmlis ukmarisoba da fankonis sindromi o o ufro xSirad pacientebSi Tirkmlis disfunqciiT anemia zidovudini ZDV o anemia da neitropenia (sustad Semcireba iTvleba normad zidovudinTan) o 1-4%, dozaze damokidebulebiT periferiuli neiropaTia didanozini, stavudini, zalcitabini cximovani atrofia stavudini, da sxva nrti o o o o kidurebis tkivili, paresTezia 10-30% wlebis Semdeg xSiria xangrZlivi gamoyenebis SemTxvevaSi (mitoqondriuli toqsiuroba) cximovani akumulacia PIs o matulobs mucelze gacximovneba, mkerdis zoma, o 20-80% o o o o o o o o o o o kreatininis monitoringi, istoria Tirkmlis daavadebis Sesaxeb mkurnaloba simto-muria tenofoviris dozis koreqcia (saWiroa kreatininis klirensi: yovel meore dRes Seicvalos tenofoviri zidovudiniT, abakaviri an stavudiniT sisxlis saerTo analizis monitoringi 2, 4, 8, 12 kviraze. makrocitozi msubuqi anemiiT (hemoglobini 100 gr/l) xSiria mkurnaloba aris eroTropoetinis transfuzia (Zalze Zviria) an Seicvalos zidovudini sxva nrti (tenofoviri, abakaviri an stavudini) periferiuli nervuli sistemis kontroli mkurnaloba tkivilis kupireba, Seicvalos arT. Sewydes wamlebi an Seicvalos nrti (zidovudini, tenofoviri, abakaviri) monitoringi da sawyis mdgom. Sedareba Seicvalos stavudini tenofoviriT an abakaviriT. Tu atrofia Seuqcevadia plastikuri qirurgia naCvenebia Sefaseba da sawyis mdgom. Sedareba Seicvalos NNRTI-iT, Tu lipodistrofia/lipoat rofia ar aris tolerantuli, naCvenebia plastikuri qirurgia nnrti>APV/fozamprenaviri FPV>abakaviriABC o makulur-papuluri gamonayari o 15% nnrti, APV 20%, abakaviri 5% transaminazebis elevacia anrti (all) da PIs (all) o auxsneli RviZlis funqciebis momateba o o 8-15% PI da nnrti ufro xSirad pacientebSi qronikuli HBV da HCV infeqciiT 51
- Page 1 and 2: aiv infeqcia/SidsiT avadmyofTa mkur
- Page 3 and 4: sarCevi klinikuri saxelmZRvanelo-re
- Page 5 and 6: 3.2.2.cxeleba aiv inficirebulebSi 3
- Page 7 and 8: aiv infeqcia/Sidsis fonze ganviTare
- Page 9 and 10: done mtkicebulebis siZlieris done (
- Page 11 and 12: 1.daavadebis definicia Sidsi abrevi
- Page 13 and 14: Sidsi registrirebulia msoflios 216
- Page 15 and 16: egistrirebul SemTxveevaTa 79% saqar
- Page 17 and 18: adamianis imunodeficitis virusis sa
- Page 19 and 20: aiv rnm-is koncentracia plazmaSi mk
- Page 21 and 22: SeuZlebelia da gadamwyveti misi dia
- Page 23 and 24: persistuli generalizebuli limfadeno
- Page 25 and 26: signalis amplifikacia komplementuri
- Page 27 and 28: • vizitamde rezistentobis testis
- Page 29 and 30: • adamianis papilomavirusi (maxvi
- Page 31 and 32: etinitis identifikaciisTvis, rodesa
- Page 33 and 34: cxrili 8 rekomendaciebi arT dawyebi
- Page 35 and 36: arv medikamentebi arseboben Semdegi
- Page 37 and 38: aCveneben, rom pirveladi rezistento
- Page 39 and 40: - tabletebis Cveneba pacientisTvis
- Page 41 and 42: - aqedan gamomdinare, nrti+anrti re
- Page 43 and 44: igulisxmeba im medikamentebis kombi
- Page 45 and 46: X (arv): testebi, romlebic unda Cat
- Page 47 and 48: maRali mgrZnobeloba abakaviri (ABC
- Page 49: transaminazebis elevacia anrti (all
- Page 53 and 54: xSiri oportonistuli infeqciebia, ma
- Page 55 and 56: cxrilebis wakiTxvis magaliTi 1. cxr
- Page 57 and 58: damateba2. jandacvis msoflio organi
- Page 59 and 60: damateba 4. ZiriTadi informacia ant
- Page 62 and 63: damateba 5. mkurnalobis reJimis dac
- Page 64 and 65: saerTaSoriso saxeli stavudini (d4T)
- Page 66 and 67: mcire mutacia muSaobs kombinaciaSi.
- Page 68 and 69: 25. Phillips AN et al. Viral load o
- Page 70 and 71: Suppl 2:S171-176. 73. Altice FL, Mo
- Page 72 and 73: 122. Koval CE et al. Immune reconst
- Page 74 and 75: kandidozi dRe yovel dRe - ko-trimoq
- Page 76 and 77: karcinoma (ara SidsTan perikardiuli
- Page 78 and 79: o cxeleba o wonaSi kleba o Ramis of
- Page 80 and 81: indikatorebi filtvis darRveuli funq
- Page 82 and 83: o yvelaze xSirad viTardeba diarea,
- Page 84 and 85: o glukokortikoidebis sistematiuri m
- Page 86 and 87: 100 mg/dReSi meore rigis sqemebi am
- Page 88 and 89: o eqspoziciis Sedegad daavadebis ga
- Page 90 and 91: o remisiis miRweva Zalian Znelia da
- Page 92 and 93: qimioTerapiiT (mag : B-ALL reJimi)
- Page 94 and 95: • imunodeficitis mqone pacientebS
- Page 96 and 97: an famcikloviri 500 mg 3-jer dReSi
- Page 98 and 99: • berkitis-tipis limfoma; • naz
ARV toqsiuroba menejmenti<br />
nefrotoqsiuroba<br />
tenofoviri TDF o Tirkmlis ukmarisoba <strong>da</strong><br />
fankonis sindromi<br />
o<br />
o<br />
ufro xSirad<br />
pacientebSi Tirkmlis<br />
disfunqciiT<br />
anemia<br />
zidovudini ZDV o anemia <strong>da</strong> neitropenia<br />
(sustad Semcireba<br />
iTvleba normad<br />
zidovudinTan)<br />
o 1-4%, dozaze<br />
<strong>da</strong>mokidebulebiT<br />
periferiuli neiropaTia<br />
di<strong>da</strong>nozini, stavudini,<br />
zalcitabini<br />
cximovani atrofia<br />
stavudini, <strong>da</strong> sxva nrti<br />
o<br />
o<br />
o<br />
o<br />
kidurebis tkivili,<br />
paresTezia<br />
10-30% wlebis Semdeg<br />
xSiria xangrZlivi<br />
gamoyenebis SemTxvevaSi<br />
(mitoqondriuli<br />
toqsiuroba)<br />
cximovani akumulacia<br />
PIs o matulobs mucelze<br />
gacximovneba, mkerdis<br />
zoma,<br />
o 20-80%<br />
o<br />
o<br />
o<br />
o<br />
o<br />
o<br />
o<br />
o<br />
o<br />
o<br />
o<br />
kreatininis monitoringi,<br />
istoria<br />
Tirkmlis <strong>da</strong>avadebis<br />
Sesaxeb<br />
<strong>mkurnaloba</strong> simto-muria<br />
tenofoviris dozis<br />
koreqcia (saWiroa<br />
kreatininis klirensi:<br />
yovel meore dRes<br />
Seicvalos tenofoviri<br />
zidovudiniT, abakaviri<br />
an stavudiniT<br />
sisxlis saerTo<br />
analizis monitoringi<br />
2, 4, 8, 12 kviraze.<br />
makrocitozi msubuqi<br />
anemiiT (hemoglobini<br />
100 gr/l) xSiria<br />
<strong>mkurnaloba</strong> aris<br />
eroTropoetinis<br />
transfuzia (Zalze<br />
Zviria) an Seicvalos<br />
zidovudini sxva nrti<br />
(tenofoviri, abakaviri<br />
an stavudini)<br />
periferiuli nervuli<br />
sistemis kontroli<br />
<strong>mkurnaloba</strong> tkivilis<br />
kupireba, Seicvalos<br />
arT. Sewydes wamlebi an<br />
Seicvalos nrti<br />
(zidovudini,<br />
tenofoviri, abakaviri)<br />
monitoringi <strong>da</strong> sawyis<br />
mdgom. Se<strong>da</strong>reba<br />
Seicvalos stavudini<br />
tenofoviriT an<br />
abakaviriT. Tu atrofia<br />
Seuqcevadia plastikuri<br />
qirurgia naCvenebia<br />
Sefaseba <strong>da</strong> sawyis<br />
mdgom. Se<strong>da</strong>reba<br />
Seicvalos NNRTI-iT,<br />
Tu<br />
lipodistrofia/lipoat<br />
rofia ar aris<br />
tolerantuli,<br />
naCvenebia plastikuri<br />
qirurgia<br />
nnrti>APV/fozamprenaviri<br />
FPV>abakaviriABC<br />
o makulur-papuluri<br />
gamonayari<br />
o 15% nnrti, APV 20%,<br />
abakaviri 5%<br />
transaminazebis elevacia<br />
anrti (all) <strong>da</strong> PIs (all) o auxsneli RviZlis<br />
funqciebis momateba<br />
o<br />
o<br />
8-15% PI <strong>da</strong> nnrti<br />
ufro xSirad<br />
pacientebSi qronikuli<br />
HBV <strong>da</strong> HCV infeqciiT<br />
51
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