aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
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pacientebSi mkurnalobis pirveli wlis ganmavlobaSi CD4 ricxvi imatebs<br />
150 /mm 3 -iT (81, 82) (AI).<br />
- Tu CD4 ricxvi ar imatebs arT <strong>da</strong>wyebi<strong>da</strong>n pirveli 9 Tvis ganmavlobaSi,<br />
ganxilul un<strong>da</strong> iqnes meore rigis arT SesaZlebloba. Tu vd<br />
aragansazRvradia, reJimi un<strong>da</strong> gagrZeldes. Tu igi > 400-1000 asli/ml-ze,<br />
un<strong>da</strong> verificirdes reJimis <strong>da</strong>cva <strong>da</strong> <strong>da</strong>iwyos meore rigis reJimi.<br />
- Tu CD4 ricxvi ar imatebs 6 Tvis ganmavlobaSi, xelaxla un<strong>da</strong> Sefasdes<br />
reJimis <strong>da</strong>cvis xarisxi.<br />
4.4.3. <strong>klinikuri</strong> araefeqturoba<br />
arT <strong>da</strong>wyebis Semdeg, oportunistuli infeqciis (oi) an sxva <strong>aiv</strong>asocirebuli<br />
<strong>da</strong>avadebis ganviTareba, <strong>klinikuri</strong> araefeqturobis<br />
indikatoria. Tumca es SeiZleba iyo imunuri rekonsitituciis sindromi<br />
(irs), gansakuTrebiT, arT-s <strong>da</strong>wyebi<strong>da</strong>n pirveli 3 Tvis ganmavlobaSi, Tu<br />
igi <strong>da</strong>wyebul iqna CD4 ricxvi 400asli/ml;<br />
>50asli/ml<br />
50 ujredi/mm 3 -ze<br />
naklebi mateba<br />
<strong>klinikuri</strong><br />
araefeqturoba<br />
oi (<strong>aiv</strong>-Tan<br />
asocirebuli)<br />
mkurnalobis<br />
<strong>da</strong>wyebi<strong>da</strong>n 12<br />
kviris Semdeg<br />
oi (gamoricxeT<br />
irs)<br />
4.5. meore rigis arv reJimi<br />
(rekomen<strong>da</strong>ciebi dozebis Sesaxeb ix. <strong>da</strong>narTi 4)<br />
- meore rigis Terapiad rekomendebulia pi-s Semcveli kombinacia. pi-ebs<br />
gaaCniaT maRali genetikuri barieri.<br />
- meore rigis arT rekomnedebulia mxolod pirveli rigis reJimis mimarT<br />
<strong>da</strong><strong>da</strong>sturebuli araefeqturobis SemTxvevaSi.<br />
- meore rigis arT <strong>da</strong>wyebasTan erTad un<strong>da</strong> moxdes reJimis <strong>da</strong>cvis<br />
xelaxali Sefaseba <strong>da</strong> maqsimaluri mxar<strong>da</strong>Wera.<br />
- meore rigis reJimis dros sul mcire ori nrti-s Secvlaa saWiro.<br />
arasodes SecvaloT mxolod erTi wamali saeWvo rezistentobis<br />
SemTxvevaSi.<br />
- efavirenzis <strong>da</strong> nevirapinis xangrZlivi naxevar<strong>da</strong>Slis periodis gamo,<br />
samive wamlis erTdrouli Sewyveta niSnavs, rom efavirenzi an nevirapini<br />
<strong>da</strong>rCeba sisxlSi nrti-ebze xangrZlivad, rac maT mimarT rezistentobis<br />
gamomwvevi mutaciis ganviTarebis risks zrdis.<br />
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